la) The MRNA transcript encoded by a gene called TLR4 has 3 EJCS (Exon Junction Complexes) bound to it, while the mRNA transcript encoded by a gene called RBBPS has 8 EJCS bound to it. What does this tell you about these two MRNAS? OA RBBPS mRNA must have more splicing enhancers than TLR4 O B. RBBPS recruited more elFs than TLR4 OC TLR4 has a shorter PolyA tail than RBBPS O D. RBBPSas more exon junctions than TLR4 OE RBBPS mRNA will be more stable and will therefore be translated more 1b) Which of the following statements is true about proteolysis? A. It is another term for RNA splicing B. It can lead to the activation of a protein C. It is a type of transcriptional modification D. It is a reversible covalent modification O E. A and B are both correct 1c) A peptide is being translated in the cytosol and immediately begins to misfold (while it is being translated) because its hydrophobic residues start to aggregate with other hydrophobic residues. In this case, which of the following proteins is not functioning properly? A. elFs B. Hsp60 O C. Proteasome O D. Calnexin/Calreticulin O E. Hsp70

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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1a)
The MRNA transcript encoded by a gene called TLR4 has 3 EJCS (Exon Junction Complexes)
bound to it, while the mRNA transcript encoded by a gene called RBBPS has 8 EJCS bound to
it. What does this tell you about these two MRNAS?
O A RBBPS MRNA must have more splicing enhancers than TLR4
O B. RBBP5 recruited more elFs than TLR4
OC TLR4 has a shorter PolyA tail than RBBPS
O D. RBBPSas more exon junctions than TLR4
O E RBBP5 MRNA will be more stable and will therefore be translated more
1b)
Which of the following statements is true about proteolysis?
A. It is another term for RNA splicing
B. It can lead to the activation of a protein
O C. It is a type of transcriptional modification
D. It is a reversible covalent modification
O E. A and B are both correct
1c)
A peptide is being translated in the cytosol and immediately begins to misfold
(while it is being translated) because its hydrophobic residues start to aggregate
with other hydrophobic residues. In this case, which of the following proteins is
not functioning properly?
O A. elFs
O B. Hsp60
O C. Proteasome
O D. Calnexin/Calreticulin
O E. Hsp70
Transcribed Image Text:1a) The MRNA transcript encoded by a gene called TLR4 has 3 EJCS (Exon Junction Complexes) bound to it, while the mRNA transcript encoded by a gene called RBBPS has 8 EJCS bound to it. What does this tell you about these two MRNAS? O A RBBPS MRNA must have more splicing enhancers than TLR4 O B. RBBP5 recruited more elFs than TLR4 OC TLR4 has a shorter PolyA tail than RBBPS O D. RBBPSas more exon junctions than TLR4 O E RBBP5 MRNA will be more stable and will therefore be translated more 1b) Which of the following statements is true about proteolysis? A. It is another term for RNA splicing B. It can lead to the activation of a protein O C. It is a type of transcriptional modification D. It is a reversible covalent modification O E. A and B are both correct 1c) A peptide is being translated in the cytosol and immediately begins to misfold (while it is being translated) because its hydrophobic residues start to aggregate with other hydrophobic residues. In this case, which of the following proteins is not functioning properly? O A. elFs O B. Hsp60 O C. Proteasome O D. Calnexin/Calreticulin O E. Hsp70
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