Kuliev and Verlinsky (2004) state that there was a relatively high number of separation errors at meiosis I. In these cases the centromere underwent a premature division, occurring at meiosis I rather than meiosis II. Regarding chromosome 21, what would you expect to be the chromosome 21 complement in the secondary oocyte in which you saw a single chromatid (monad) for chromosome 21 in the first polar body? If this secondary oocyte was involved in fertilization, what would be the expected consequences?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
Section: Chapter Questions
Problem 16QP: Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies...
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Kuliev and Verlinsky (2004) state that there was a relatively
high number of separation errors at meiosis I. In these cases the
centromere underwent a premature division, occurring at meiosis
I rather than meiosis II. Regarding chromosome 21, what
would you expect to be the chromosome 21 complement in the
secondary oocyte in which you saw a single chromatid (monad)
for chromosome 21 in the first polar body? If this secondary
oocyte was involved in fertilization, what would be the expected
consequences?

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