Homework Help is Here – Start Your Trial Now!
Science
Chemistry
Justify your answer with calculations of partial charges on these amino acid side chains at pH = 7.8. (Hint: Consider lessons from Coulomb's law, and the Henderson-Hasselbalch equation.) Express your answers using two significant figures separated by a comma. Π| ΑΣΦ - 0.99,0.04 Submit Previous Answers Request Answer ? Incorrect: Try Again: 3 attempts remaining

Justify your answer with calculations of partial charges on these amino acid side chains at pH = 7.8. (Hint: Consider lessons from Coulomb's law, and the Henderson-Hasselbalch equation.) Express your answers using two significant figures separated by a comma. Π| ΑΣΦ - 0.99,0.04 Submit Previous Answers Request Answer ? Incorrect: Try Again: 3 attempts remaining

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
See similar textbooks
icon
Related questions
Question

answer part C/last question only. box the answer and MAKE SURE IT IS CORRECT

Justify your answer with calculations of partial charges on these amino acid side chains at pH = 7.8. (Hint: Consider lessons from Coulomb's law, and the Henderson-Hasselbalch equation.) Express your answers using two significant figures separated by a comma. ΑΣΦ - 0.99.0.04 Submit www. ]] ? Previous Answers Request Answer Incorrect: Try Again: 3 attempts remaining
Transcribed Image Text:Justify your answer with calculations of partial charges on these amino acid side chains at pH = 7.8. (Hint: Consider lessons from Coulomb's law, and the Henderson-Hasselbalch equation.) Express your answers using two significant figures separated by a comma. ΑΣΦ - 0.99.0.04 Submit www. ]] ? Previous Answers Request Answer Incorrect: Try Again: 3 attempts remaining
Part A Do you predict that this salt bridge will become stronger, become weaker, or be unaffected as pH increases from pH = 7.2 to pH = 7.8? O The salt bridge will become stronger. The salt bridge will become weaker. The salt bridge will be unaffected. Submit ✓ Correct At pH = 7.2 the glutamic acid (Glu) side chain will carry a charge of ~ -1 (at 3 pH units above the pK₂ for Glu, the side chain will be almost fully ionized); whereas the histidine (His) side chain will carry a charge of < +0.5 (at pH=pKa the charge on His would be +0.5; since pH = 7.2 is above its pKa, it will carry less (+) charge as it becomes more deprotonated). As the pH increase to 7.8, the charge on Glu will remain ~ -1 and the charge on His will decrease; thus, this salt bridge is predicted to become weaker as pH is raised from 7.2 to 7.8. Part B Previous Answers Justify your answer with calculations of partial charges on these amino acid side chains at pH = 7.2. (Hint: Consider lessons from Coulomb's law, and the Henderson-Hasselbalch equation.) Express your answers using two significant figures separated by a comma. -1.0,0.17 Submit Previous Answers
Transcribed Image Text:Part A Do you predict that this salt bridge will become stronger, become weaker, or be unaffected as pH increases from pH = 7.2 to pH = 7.8? O The salt bridge will become stronger. The salt bridge will become weaker. The salt bridge will be unaffected. Submit ✓ Correct At pH = 7.2 the glutamic acid (Glu) side chain will carry a charge of ~ -1 (at 3 pH units above the pK₂ for Glu, the side chain will be almost fully ionized); whereas the histidine (His) side chain will carry a charge of < +0.5 (at pH=pKa the charge on His would be +0.5; since pH = 7.2 is above its pKa, it will carry less (+) charge as it becomes more deprotonated). As the pH increase to 7.8, the charge on Glu will remain ~ -1 and the charge on His will decrease; thus, this salt bridge is predicted to become weaker as pH is raised from 7.2 to 7.8. Part B Previous Answers Justify your answer with calculations of partial charges on these amino acid side chains at pH = 7.2. (Hint: Consider lessons from Coulomb's law, and the Henderson-Hasselbalch equation.) Express your answers using two significant figures separated by a comma. -1.0,0.17 Submit Previous Answers
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps with 1 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Applications of Molecular Spectroscopy
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY
SEE MORE TEXTBOOKS