Iron is an essential nutrient. Iron deficiency has beenlinked with symptoms such as anemia, rapid heartbeat,increased risk of infections, and lightheadedness. At theother end of the spectrum is iron overload, describedin an August 2012 New York Times article. Excess ironis deposited in the liver, heart, and pancreas and cancause cirrhosis, liver cancer, cardiac arrhythmias, anddiabetes. According to a Framingham Heart Studyresearcher, “About one person in 250 inherits a geneticdisorder called hemochromatosis that increases ironabsorption and results in a gradual, organ-damagingbuildup of stored iron.” Suppose we have a random sample of 1000 adults, and want to find the probabil-ity that at least 5 of them have this disorder. Which of these statements is true? I. We would expect 4 of these people to have hemo-chromatosis. II. We can calculate this probability using a Binomialmodel.III. We can approximate this probability using a Normalmodel.A) None B) I only C) I and II onlyD) I and III only E) I, II, and III

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Iron is an essential nutrient. Iron deficiency has been
linked with symptoms such as anemia, rapid heartbeat,
increased risk of infections, and lightheadedness. At the
other end of the spectrum is iron overload, described
in an August 2012 New York Times article. Excess iron
is deposited in the liver, heart, and pancreas and can
cause cirrhosis, liver cancer, cardiac arrhythmias, and
diabetes. According to a Framingham Heart Study
researcher, “About one person in 250 inherits a genetic
disorder called hemochromatosis that increases iron
absorption and results in a gradual, organ-damaging
buildup of stored iron.” Suppose we have a random
sample of 1000 adults, and want to find the probabil-
ity that at least 5 of them have this disorder. Which of
these statements is true?
I. We would expect 4 of these people to have hemo-
chromatosis.
II. We can calculate this probability using a Binomial
model.
III. We can approximate this probability using a Normal
model.
A) None B) I only C) I and II only
D) I and III only E) I, II, and III
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