Intact immunoglobulins as well as free light chains may form multimers. In addition to complicating the interpretation of SPEP and SIFE, multimeric light chains are important in the pathogenesis of: Lytic bone lesions Amyloidosis Hyper-viscosity syndrome Hypogammaglobinemia Hemolytic anemia

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 14RE
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Intact immunoglobulins as well as free light
chains may form multimers. In addition to
complicating the interpretation of SPEP and
SIFE, multimeric light chains are important in the
pathogenesis of:
Lytic bone lesions
Amyloidosis
Hyper-viscosity syndrome
Hypogammaglobinemia
Hemolytic anemia
Transcribed Image Text:Intact immunoglobulins as well as free light chains may form multimers. In addition to complicating the interpretation of SPEP and SIFE, multimeric light chains are important in the pathogenesis of: Lytic bone lesions Amyloidosis Hyper-viscosity syndrome Hypogammaglobinemia Hemolytic anemia
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