Intact immunoglobulins as well as free light chains may form multimers. In addition to complicating the interpretation of SPEP and SIFE, multimeric light chains are important in the pathogenesis of: Lytic bone lesions Amyloidosis Hyper-viscosity syndrome Hypogammaglobinemia Hemolytic anemia

Intact immunoglobulins as well as free light chains may form multimers. In addition to complicating the interpretation of SPEP and SIFE, multimeric light chains are important in the pathogenesis of: Lytic bone lesions Amyloidosis Hyper-viscosity syndrome Hypogammaglobinemia Hemolytic anemia

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter12: Body Defenses

Section: Chapter Questions

Problem 14RE

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Concept explainers

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.

Question

Written answer with explanation only

Intact immunoglobulins as well as free light
chains may form multimers. In addition to
complicating the interpretation of SPEP and
SIFE, multimeric light chains are important in the
pathogenesis of:
Lytic bone lesions
Amyloidosis
Hyper-viscosity syndrome
Hypogammaglobinemia
Hemolytic anemia

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