Indicate which of the four major classes of rearrangements (deletion, duplication, inversions, and translocations) are most likely to be associated with each of the following phenomena. In each case, explain the effect. a. Semisterility b. Lethality c. Vulnerability to mutation d. Haploinsufficiency e. Hypermorphic mutation (a gain of function mutation that causes an increase in otherwise normal gene function) f. Crossover suppression g. Aneuploidy

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Indicate which of the four major classes of rearrangements (deletion, duplication, inversions, and translocations) are most likely to be associated with each of the following phenomena. In each case, explain the effect. a. Semisterility b. Lethality c. Vulnerability to mutation d. Haploinsufficiency e. Hypermorphic mutation (a gain of function mutation that causes an increase in otherwise normal gene function) f. Crossover suppression g. Aneuploidy
Review
Indicate which of the four major classes of rearrangements
(deletion, duplication, inversions, and translocations) are most
likely to be associated with each of the following phenomena. In
each case, explain the effect.
Semisterility
Lethality
Vulnerability to mutation
Haploinsufficiency
Hypermorphic mutation (a gain of function mutation that causes
an increase in otherwise normal gene function)
a.
b.
с.
d.
е.
Crossover suppression
f.
Aneuploidy
g.
Transcribed Image Text:Review Indicate which of the four major classes of rearrangements (deletion, duplication, inversions, and translocations) are most likely to be associated with each of the following phenomena. In each case, explain the effect. Semisterility Lethality Vulnerability to mutation Haploinsufficiency Hypermorphic mutation (a gain of function mutation that causes an increase in otherwise normal gene function) a. b. с. d. е. Crossover suppression f. Aneuploidy g.
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