In response to high blood Ca2+ parathyroid hormone secretion willand calcitonin secretion will|decrease, decreasedecrease, increaseincrease, increase

Answered: In response to high blood Ca2+…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

In response to high blood Ca2+ parathyroid hormone secretion will
and calcitonin secretion will|
decrease, decrease
decrease, increase
increase, increase

Expert Solution

Step 1

The parathyroid gland produces parathyroid hormone, which is a polypeptide that is produced and cleaved into an active form. A pre-pro-PTH, a 115-amino-acid polypeptide, is synthesized first, then cleaved to generate pro-PTH, which is 90-amino-acids long. It is subsequently cleaved a second time, this time at the amino-terminal end, to provide 84 amino acid active parathyroid hormone. This is the most important hormone in the body since it is stored, secreted, and operates. Synthesis, cleavage, and storage are all expected to take less than an hour.