In randomized, double-blind clinical trials of a new vaccine, rats were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 104 of 699 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 61 of 580 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the a=0.05 level of significance? Verify the model requirements. Select all that apply. A. The samples are independent. B. The data come from a population that is normally distributed C. The sample size is less than 5% of the population size for each sample. D.P₁ (1-₁) 2 ≥ 10 and E. The samples are dependent. F. The sample size is more than 5% of the population size for each sample. Determine the null and alternative hypotheses. Ho P1 P2 H₁ P₁ P₂ Find the test statistic for this hypothesis test. 2.32 (Round to two decimal places as needed.) Determine the P-value for this hypothesis test. 10₂P₂ (1-P₂) ≥10

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**Clinical Trial Analysis of a New Vaccine**

In a randomized, double-blind clinical trial of a new vaccine, rats were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 104 of 699 subjects in the experimental group (group 1) experienced drowsiness as a side effect. In the control group (group 2), 61 of 580 subjects experienced drowsiness after the second dose.

**Research Question:**
Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α = 0.05 level of significance?

**Model Requirements Verification**
Select all that apply:
- [x] A. The samples are independent.
- [ ] B. The data come from a population that is normally distributed.
- [x] C. The sample size is less than 5% of the population size for each sample.
- [x] D. \( n_1 \hat{p}_1 (1 - \hat{p}_1) \geq 10 \) and \( n_2 \hat{p}_2 (1 - \hat{p}_2) \geq 10 \)
- [ ] E. The samples are dependent.
- [ ] F. The sample size is more than 5% of the population size for each sample.

**Hypotheses:**

- Null Hypothesis (\( H_0 \)): \( p_1 = p_2 \)
- Alternative Hypothesis (\( H_1 \)): \( p_1 > p_2 \)

**Test Statistic:**
The test statistic for this hypothesis test is calculated to be 2.32 (rounded to two decimal places).

**P-value Determination:**
Calculate the P-value for this hypothesis test based on the test statistic.
Transcribed Image Text:**Clinical Trial Analysis of a New Vaccine** In a randomized, double-blind clinical trial of a new vaccine, rats were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 104 of 699 subjects in the experimental group (group 1) experienced drowsiness as a side effect. In the control group (group 2), 61 of 580 subjects experienced drowsiness after the second dose. **Research Question:** Does the evidence suggest that a higher proportion of subjects in group 1 experienced drowsiness as a side effect than subjects in group 2 at the α = 0.05 level of significance? **Model Requirements Verification** Select all that apply: - [x] A. The samples are independent. - [ ] B. The data come from a population that is normally distributed. - [x] C. The sample size is less than 5% of the population size for each sample. - [x] D. \( n_1 \hat{p}_1 (1 - \hat{p}_1) \geq 10 \) and \( n_2 \hat{p}_2 (1 - \hat{p}_2) \geq 10 \) - [ ] E. The samples are dependent. - [ ] F. The sample size is more than 5% of the population size for each sample. **Hypotheses:** - Null Hypothesis (\( H_0 \)): \( p_1 = p_2 \) - Alternative Hypothesis (\( H_1 \)): \( p_1 > p_2 \) **Test Statistic:** The test statistic for this hypothesis test is calculated to be 2.32 (rounded to two decimal places). **P-value Determination:** Calculate the P-value for this hypothesis test based on the test statistic.
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