In chromosomes, doubly-stranded DNA wraps tightly around histone proteins. Think about the structure of DNA, especially the "backbone," and determine what category of amino acids make up the majority of histones: Histone Octamer tetramer dimer dimer dimer dimer Histone "fastener Here the blue represents histones, and the red is the DNA strand. To help the DNA fold up in an aqueous environment, the histones are nonpolar to exclude water, so many of the amino acid side chains are nonpolar. O The backbone of DNA is the alternating phosphate-sugar part, and the phosphate is negatively charged. Positive charges on the histone residues will bind tightly here, so the acidic amino acids are used here. O The backbone of DNA is the alternating phosphate-deoxyribose part, and the phosphate is negatively charged. Positive charges on the histone residues will bind tightly here, so the basic amino acids are used here. The histones are strongly attracted to the hydrogen-bonding of the base pairs, so the side chains should come from polar (but uncharged) amino acids. tetramer

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In chromosomes, doubly-stranded DNA wraps tightly around histone proteins. Think about the structure of DNA, especially the "backbone," and determine what category of
amino acids make up the majority of histones:
Histone Octamer
tetramer
dimer HZA
dimer
dimer
dimer
Histone "fastener"
Here the blue represents histones, and the red is the DNA strand.
To help the DNA fold up in an aqueous environment, the histones are nonpolar to exclude water, so many of the amino acid side chains are nonpolar.
The backbone of DNA is the alternating phosphate-sugar part, and the phosphate is negatively charged. Positive charges on the histone residues will bind tightly here, so
the acidic amino acids are used here.
The backbone of DNA is the alternating phosphate-deoxyribose part, and the phosphate is negatively charged. Positive charges on the histone residues will bind tightly
here, so the basic amino acids are used here.
The histones are strongly attracted to the hydrogen-bonding of the base pairs, so the side chains should come from polar (but uncharged) amino acids.
tetramer
Transcribed Image Text:In chromosomes, doubly-stranded DNA wraps tightly around histone proteins. Think about the structure of DNA, especially the "backbone," and determine what category of amino acids make up the majority of histones: Histone Octamer tetramer dimer HZA dimer dimer dimer Histone "fastener" Here the blue represents histones, and the red is the DNA strand. To help the DNA fold up in an aqueous environment, the histones are nonpolar to exclude water, so many of the amino acid side chains are nonpolar. The backbone of DNA is the alternating phosphate-sugar part, and the phosphate is negatively charged. Positive charges on the histone residues will bind tightly here, so the acidic amino acids are used here. The backbone of DNA is the alternating phosphate-deoxyribose part, and the phosphate is negatively charged. Positive charges on the histone residues will bind tightly here, so the basic amino acids are used here. The histones are strongly attracted to the hydrogen-bonding of the base pairs, so the side chains should come from polar (but uncharged) amino acids. tetramer
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