In ATP synthase, what is the importance of the beta subunit, and how does it interact with the gamma subunit, as well as how does gamma interacts with the c ring.
In ATP synthase, what is the importance of the beta subunit, and how does it interact with the gamma subunit, as well as how does gamma interacts with the c ring.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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In ATP synthase, what is the importance of the beta subunit, and how does it interact with the gamma subunit, as well as how does gamma interacts with the c ring.
Expert Solution
ATP synthase
As per the chemiosmotic model, the proton motive force drives the ATP synthesis. ATP synthase is the enzyme that uses the energy stored in the proton gradient to produce ATP from ADP and Pi. ATP synthase has two domains F1 and F0. F0 has a pore through which protons 'leak'. By the rotational catalysis mechanism, three active sites of F1 take turns catalysing ATP synthesis from ADP and Pi.
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