In an ethnic population, there is a constant prevalence of familial hypercholesterolemia with frequency of 1 in 4000 individuals having a severe form and 1 in 32 a mild form. Familial hypercholesterolemia is a genetic disease with an incomplete dominant inheritance pattern in which the severe cases are homozygous mutant and the mild cases are heterozygous. Based on this information: (i.) Is the population in the Hardy- Weinberg equilibrium? (ii.) Taking this into consideration, what is the closet estimate f the chance that a newly born baby (in the next generation) will not develop any form of

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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In an ethnic population, there is a constant prevalence of familial hypercholesterolemia
with frequency of 1 in 4000 individuals having a severe form and 1 in 32 a mild form.
Familial hypercholesterolemia is a genetic disease with an incomplete dominant
inheritance pattern in which the severe cases are homozygous mutant and the mild
cases are heterozygous. Based on this information: (i.) Is the population in the Hardy-
Weinberg equilibrium? (ii.) Taking this into consideration, what is the closet estimate f
the chance that a newly born baby (in the next generation) will not develop any form of
hypercholesterolemia?
Transcribed Image Text:In an ethnic population, there is a constant prevalence of familial hypercholesterolemia with frequency of 1 in 4000 individuals having a severe form and 1 in 32 a mild form. Familial hypercholesterolemia is a genetic disease with an incomplete dominant inheritance pattern in which the severe cases are homozygous mutant and the mild cases are heterozygous. Based on this information: (i.) Is the population in the Hardy- Weinberg equilibrium? (ii.) Taking this into consideration, what is the closet estimate f the chance that a newly born baby (in the next generation) will not develop any form of hypercholesterolemia?
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