In a simple synapse, neurotransmitter chemicals are released by ______ Select one: A. the presynaptic membrane B. ducts on the smooth endoplasmic reticulum C. axon hillocks D. cell bodies
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- Given the steps shown below, which of the following is the correct sequence for transmission at a chemical synapse? 1. neurotransmitter binds with receptor 2. sodium ions rush into neuron's cytoplasm 3. action potential depolarizes the presynaptic membrane 4. ion channel opens to allow particular ion to enter cell 5. synaptic vesicles release neurotransmitter into the synaptic cleft O 1, 2, 3, 4, 5 O 5, 1, 2, 4, 3 O 2, 3, 5, 4, 1 O4, 3, 1, 2, 5 O 3, 2, 5, 1, 4The following steps refer to various stages in transmission at a chemical synapse. 1. Neurotransmitter binds with receptors associated with the postsynaptic membrane. 2. Calcium ions rush into neuron's cytoplasm. 3. An action potential depolarizes the membrane of the presynaptic axon terminal. 4. The ligand-gated ion channels open. 5. The synaptic vesicles release neurotransmitter into the synaptic cleft. Which step occurs first in transmission at a chemical synapse? Ostep 1 occurs first step 2 occurs first step 3 occurs first step 4 occurs first Ostep 5 occurs firstRegardless of type, all neurons transfer signals between each other or to effectors (muscles or glands) at a synapse. The neuromuscular junction that we talked about with the muscular system is one example of a synapse. The diagram below shows the general features of a synapse Match each term or description with the appropriate letter in the diagram. You may use terms more than once. 1. Synaptic knob in axon terminal of pre-synaptic cell: 2. Synaptic cleft: 3. Neurotransmitter: 4. Dendrite of post-synaptic cell: 5. Cell body of post-synaptic cell: 6. Receptor in plasma membrane of post-synaptic cell: 7. Chemical released by neurons that stimulates or inhibits other neurons, muscles, or glands: 8. Cell that sends the signal: 9. Dendrite of cell that receives the signal: 10. Space between cells that must be crossed by neurotransmitters: 11. Structure that opens, like a "protein door", when neurotransmitters attach to it:
- Some postsynaptic synapses are called silent synapses due to the lack of AMPA receptors. Why do those synapses not have a synaptic response at the resting membrane potential? Explain under what conditions you would still be able to detect a postsynaptic response from those silent synapses.Synaptic transmission depends upon :- a-direct transmission of impulses from the presynaptic neuron to the postsynaptic neuronb- diffusion of neurotransmitters from synaptic knobs into the soma and dendrites of postsynaptic neuronsc- presence of voltage-gated Ca ++ channels in membrane of synaptic knobsd- presence of voltage-gated Ca ++ channels in the subsynaptic membraneA synapse consists of: a. a synaptic knob b. neuron cell body c. plasma membrane of post synaptic neuron d. a synaptic knob, synaptic cleft, and plasma membrane of post synaptic neuron
- In chemical synapses, transmission occurs in a forward direction because :-a- neurotransmitter receptors are found only in the postsynaptic membraneb- the subsynaptic membrane does not contain neurotransmitter vesiclesc- the subsynaptic membrane is more sensitive than the membrane of synaptic knob to the effect of neurotransmittersd- the subsynaptic membrane contains both ligand-gated and voltage-gated ionic channelsYou are recording from two neurons in order to characterize the synapse that connects them. When the presynaptic neuron (Neuron A) fires an action potential, the postsynaptic neuron (Neuron B) is rapidly depolarized. You suspect that the synapse is electrical, and carry out the following experiments to test your hypothesis. A. When you try the converse experiment, and fıre an action potential in the Neuron B, you see a depolarization in the Neuron A. Based on your understanding of the different kinds of synaptic transmission does this support your hypothesis?Besides the standard post- and pre-synapse that exchange information, non neuronal cell types also play a role in synaptic transmission. One of those are called astrocytes and can form a tripartite synapse. Explain the roles of astrocytes in synaptic transmission.
- All of the following statements correctly describe a polarized membrane EXCEPT which? a. There is a separation of the charge by a membrane, resulting in its ability to do work. b. An RMP of –60 mV indicates that there are more positive ions inside the axon than an RMP of –70 mV. c. A resting membrane potential (RMP) of –90 mV indicates the there are more positive ions inside the axon than an RMP of –70 mV. d. There is a difference in the charges found on the inside of the membrane to the outside.An undisclosed drug (Drug A) is a drug that can block voltage-gated K+ channels when being introduced into the bloodstream. Explain the effects of Drug A on the action potentials produced by a neuron. If Drug A could be applied selectively to a presynaptic neuron that releases an excitatory neurotransmitter, analyse how would it alter the synaptic effect of the neurotransmitter on the presynaptic cell. Remark: The word count limit (250 words only), no less than 100 wordswhich one of the following statements is incorrect? a. temporal summation occurs when a single synaptic input is activated twice in succession, with the second postsynaptic potential occurring before the first postsynaptic potential is over. b. blocking voltage-gated k* channels in the presynaptic membrane of a typical chemical synapse is likely to reduce the amount of neurotransmitter released in response to a single action potential in the presynaptic axon. c. in the optic tectum of the hunting rattlesnake, spatial summation is used to combine inputs from visual and thermoreceptive layers in order to make a decision whether to strike at a mouse-like object. d. a single type of neurotransmitter can have different postsynaptic actions depending on the type of receptor to which it binds.