In a case-control study, 317 patients suffering from endometrial cancer were matched individually with 317 other cancer patients in a hospital and the use of estrogen in the six months prior to diagnosis was determined. Estrogen is associated with several types of cancer. The findings are shown below: Cases Estrogen 67 25 Controls No estrogen 143 Estrogen No estrogen 180 i. State the null and alternative hypothesis ii. Perform the appropriate test of significance mO of a particulan

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Author:Amos Gilat
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In a case-control study, 317 patients suffering from endometrial cancer were
matched individually with 317 other cancer patients in a hospital and the use of
estrogen in the six months prior to diagnosis was determined. Estrogen is
associated with several types of cancer. The findings are shown below:
Controls
No estrogen
143
180
Cases
Estrogen
No estrogen
Estrogen
67
25
i State the null and alternative hypothesis
Perform the appropriate test of significance
ii.
b) In a genetics experiment, investigators looked at 300 chromosomes of a particular
type and counted the number of sister-chromatid exchanges on each. A Poisson
model was hypothesized for the distribution of the number of exchanges. Was
the hypothesis valid given the data below:
Number of exchanges
3
4.
6.
7.
8.
9.
6.
24
42
59
62
44
41
14
Counts
2.
6.
く
Transcribed Image Text:In a case-control study, 317 patients suffering from endometrial cancer were matched individually with 317 other cancer patients in a hospital and the use of estrogen in the six months prior to diagnosis was determined. Estrogen is associated with several types of cancer. The findings are shown below: Controls No estrogen 143 180 Cases Estrogen No estrogen Estrogen 67 25 i State the null and alternative hypothesis Perform the appropriate test of significance ii. b) In a genetics experiment, investigators looked at 300 chromosomes of a particular type and counted the number of sister-chromatid exchanges on each. A Poisson model was hypothesized for the distribution of the number of exchanges. Was the hypothesis valid given the data below: Number of exchanges 3 4. 6. 7. 8. 9. 6. 24 42 59 62 44 41 14 Counts 2. 6. く
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