(ii)Predict the heterocyclic product(s) M from the following reaction with substrate L. Show acurly arrow mechanism and explain the regioselectivity of the reaction.12,0PHÍ NHNHNO3/H₂SO4Propose a structure for intermediate P and propose reagents for its synthesis from amide N.Draw a curly arrow mechanism for the conversion of P into the thiazole shown.NH₂MP-Ph

In pyridine-N-oxide 2 and 4 position is prone towards electrophilic attack Amides are converted to…

(ii) (iii) Predict the heterocyclic product(s) M from the following reaction with substrate L. Show a curly arrow mechanism and explain the regioselectivity of the reaction. Ph Propose a structure for intermediate P and propose reagents for its synthesis from amide N. Draw a curly arrow mechanism for the conversion of P into the thiazole shown. 0= z HNO3/H₂SO4 NH₂ M CI- -Ph

(ii) (iii) Predict the heterocyclic product(s) M from the following reaction with substrate L. Show a curly arrow mechanism and explain the regioselectivity of the reaction. Ph Propose a structure for intermediate P and propose reagents for its synthesis from amide N. Draw a curly arrow mechanism for the conversion of P into the thiazole shown. 0= z HNO3/H₂SO4 NH₂ M CI- -Ph

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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