(i) Identify a-protons in compound H, estimate their pKa values and draw the structure for the two different enolates that could form under basic conditions. Explain why one enolate is more stable than the other. Eto (ii) Show the structure of mono-alkylation product J and give a mechanism for its formation. Explain why NaOMe would not be a suitable base for this reaction. OEt mechanisms. Br NaOEt H Ph OEt (1) NaOH(aq) (2) Acidify HO K Ph (iii) In the subsequent step adduct J is converted into carboxylic acid K under the conditions given. Explain this decarboxylation process that occurs when heating using curly arrow

(i) Identify a-protons in compound H, estimate their pKa values and draw the structure for the two different enolates that could form under basic conditions. Explain why one enolate is more stable than the other. Eto (ii) Show the structure of mono-alkylation product J and give a mechanism for its formation. Explain why NaOMe would not be a suitable base for this reaction. OEt mechanisms. Br NaOEt H Ph OEt (1) NaOH(aq) (2) Acidify HO K Ph (iii) In the subsequent step adduct J is converted into carboxylic acid K under the conditions given. Explain this decarboxylation process that occurs when heating using curly arrow

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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