If a cylindrical stirred tank bioreactor is scaled up from 1 L to 10,000 L at constant tip impeller speed, what would be the ratio (larger / smaller bioreactor) for the following operating parameters: a) agitation rate? b) power per volume? c) liquid pumping per volume? You may assume that geometric similarity is maintained during scale-up.
If a cylindrical stirred tank bioreactor is scaled up from 1 L to 10,000 L at constant tip impeller speed, what would be the ratio (larger / smaller bioreactor) for the following operating parameters: a) agitation rate? b) power per volume? c) liquid pumping per volume? You may assume that geometric similarity is maintained during scale-up.
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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Transcribed Image Text:If a cylindrical stirred tank bioreactor is scaled up from 1 L to 10,000 L at constant tip impeller speed, what
would be the ratio (larger / smaller bioreactor) for the following operating parameters:
a) agitation rate?
b) power per volume?
c) liquid pumping per volume?
You may assume that geometric similarity is maintained during scale-up.
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