How would you separate a racemic mixture of (R)-1-phenylethan-1-amine and (S)-1-phenylethan-1- amine? NH₂ (S)-1-phenylethan-1-amine (R)-1-phenylethan-1-amine *more than one answer works! NH₂ use filter paper and a funnel O add pure (R)-2-hydroxysuccinic acid to make a pair of diastereomeric salts that can be separated physically Odo column chromatography with an achiral adsorption agent, like alumina add pure (S)-2-hydroxysuccinic acid to make a pair of diastereomeric salts that can be separated physically Do column chromatography with a chiral adsorption agent. O add a racemic mixture of (R)- and (S)-2-hydroxysuccinic acid and obtain two diastereomeric pairs of enantiomeric salts. (now you have 4 components to separate! YAY!)
How would you separate a racemic mixture of (R)-1-phenylethan-1-amine and (S)-1-phenylethan-1- amine? NH₂ (S)-1-phenylethan-1-amine (R)-1-phenylethan-1-amine *more than one answer works! NH₂ use filter paper and a funnel O add pure (R)-2-hydroxysuccinic acid to make a pair of diastereomeric salts that can be separated physically Odo column chromatography with an achiral adsorption agent, like alumina add pure (S)-2-hydroxysuccinic acid to make a pair of diastereomeric salts that can be separated physically Do column chromatography with a chiral adsorption agent. O add a racemic mixture of (R)- and (S)-2-hydroxysuccinic acid and obtain two diastereomeric pairs of enantiomeric salts. (now you have 4 components to separate! YAY!)
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:How would you separate a racemic mixture of (R)-1-phenylethan-1-amine and (S)-1-phenylethan-1-
amine?
NH₂
(S)-1-phenylethan-1-amine
(R)-1-phenylethan-1-amine
*more than one answer works!
NH₂
O use filter paper and a funnel
O add pure (R)-2-hydroxysuccinic acid to make a pair of diastereomeric salts that can be separated physically
O do column chromatography with an achiral adsorption agent, like alumina
add pure (S)-2-hydroxysuccinic acid to make a pair of diastereomeric salts that can be separated physically
O Do column chromatography with a chiral adsorption agent.
add a racemic mixture of (R)- and (S)-2-hydroxysuccinic acid and obtain two diastereomeric pairs of
enantiomeric salts. (now you have 4 components to separate! YAY!)
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