How many RNA primers are need for the leading

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
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Author:Michael Cummings
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Chapter11: Genome Alterations: Mutation And Epigenetics
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Problem 18QP: Replication involves a period of time during which DNA is particularly susceptible to the...
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### Understanding RNA Primers in DNA Replication

During DNA replication, RNA primers are essential for initiating the synthesis of new DNA strands. They provide a starting point for DNA polymerase to begin adding nucleotides.

#### How many RNA primers are needed for the leading strand? 

The leading strand requires only one RNA primer at the origin of replication. This is because it undergoes continuous synthesis in the 5' to 3' direction following the movement of the replication fork.

#### How many RNA primers are needed for the lagging strand?

The lagging strand, on the other hand, requires multiple RNA primers. This strand is synthesized discontinuously in small segments known as Okazaki fragments. Each Okazaki fragment starts with a new RNA primer, meaning that multiple primers are necessary along the length of the lagging strand.

Understanding the different needs for RNA primers in leading and lagging strands highlights the asymmetry in the DNA replication process and is fundamental to comprehending molecular biology and genetics.
Transcribed Image Text:### Understanding RNA Primers in DNA Replication During DNA replication, RNA primers are essential for initiating the synthesis of new DNA strands. They provide a starting point for DNA polymerase to begin adding nucleotides. #### How many RNA primers are needed for the leading strand? The leading strand requires only one RNA primer at the origin of replication. This is because it undergoes continuous synthesis in the 5' to 3' direction following the movement of the replication fork. #### How many RNA primers are needed for the lagging strand? The lagging strand, on the other hand, requires multiple RNA primers. This strand is synthesized discontinuously in small segments known as Okazaki fragments. Each Okazaki fragment starts with a new RNA primer, meaning that multiple primers are necessary along the length of the lagging strand. Understanding the different needs for RNA primers in leading and lagging strands highlights the asymmetry in the DNA replication process and is fundamental to comprehending molecular biology and genetics.
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