How does hydroxyurea therapy alleviate the symptoms of sicklecell anemia?(Select all that apply.)HbS dilutes HbF and thus somewhat relieves thesymptoms of the disease.HbF dilutes HbS and thus somewhat relieves thesymptoms of the disease.HbF, because of its amino acid sequence, does notsickle and clog capillaries.O Hydroxyurea enhances the production of sickle-cellhemoglobin (HbS) in the bone marrow.Hydroxyurea enhances the production of fetalhemoglobin (HbF) in the bone marrow.O HbS, because of its amino acid sequence, does notsickle and clog capillaries.

The question is about therapy that allevate the treatment for sickle cell anaemia, the hydroxyurea…

Answered: How does hydroxyurea therapy alleviate…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

I know that hemoglobin has cooperative binding what about hemocyanin does it have cooperative binding
Please solve the fifth question to this problem.
Type I diabetes is caused by destruction of the beta cells of the pancreas, the cells that produce insulin. In most cases, the beta cells are destroyed by an immune response. Both genetic and environmental factors are involved in triggering the immune response. NOD mice develop a disease very much like Type I diabetes. (NOD mouse = non-obese, diabetic, mouse). If you transfer plasma from a NOD mouse to a normal mouse, the normal is not affected. If you transfer lymphocytes (WBCs white blood cells) from a NOD mouse, the normal mouse develops diabetes. The first people to figure this out found they had to transfer two types of WBC to transfer diabetes. After some experiments, they found that under the right conditions, they only had to transfer one type of cell to cause diabetes in the recipient. B-1. Consider the one type of WBC that can cause diabetes by itself. Which type is it likely to be? (B cells) (helper T cells) (cytotoxic T cells) (either type of T cell) (any of these)…
The doctor also mentioned a new treatment for Sickle Cell Disease to JJ called Voxelotor (Oxbryta). Voxelotor binds to the a-globin chain and alters the structure of HbS stabilizing it in the R-state (relaxed state). Q7: In the presence of Voxelotor would you expect the affinity of HbS for O2 to increase or decrease? Q8: How would you classify the mechanism of action for Voxelotor?
Vitamin B12 cannot be produced by the human body but instead must be obtained from your diet. A patient has a diagnosis of pernicious anemia (Megaloblastic anemia). Explain the most common underlying cause of this disorder and explain how it is treated?
Regarding cardiovascular disease, match each tern A condition marked by edema of the lungs and shortness of breath, especially when lying down A lesion often seen on the retinal surface (in the eye) of people with diabetes and/or hypertension A triglyceride produced in the liver in response to a high carbohydrate diet that increases chronic disease risk A macrophage that has become engorged with indigestible lipid molecules, leading to inflammation [Choose ] [Choose ] [Choose ] [Choose ] the phrase best describes it
Answer is NOT D Help
a. How many subunits does hemoglobin have? What are their conventional names? b. Identify the oxygen binding sites on hemoglobin. How many oxygens can one molecule of hemoglobin bind? How many oxygens can one subunit of hemoglobin bind? c. Identify the central cavity of hemoglobin. Is it the same or different than the oxygen binding site of hemoglobin?
critically analyse in detail the diffrences and similarities of iron deffiency and thalassemia in regards ot microsytic and macrosytic anemia.
Hemoglobin is an enzyme containing amino acids linked by peptide bonds. Select one: True False
What is the role of copper in the Fenton reaction? Why is free copper harmful to the body? Most body copper is carried in the plasma. What is the physiological implication? What is the link between copper and atherosclerosis? How penicillamine works as a treatment for copper overload?

Recommended textbooks for you

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781305961135

Author:

Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:

Cengage Learning

Biochemistry

ISBN:

9781305577206

Author:

Reginald H. Garrett, Charles M. Grisham

Publisher:

Cengage Learning

Fundamentals of General, Organic, and Biological …

Biochemistry

ISBN:

9780134015187

Author:

John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson

Publisher:

PEARSON

SEE MORE TEXTBOOKS