Hookworms, parasitic nematodes transmitted through contact between bare feet and soil, infect nearly a half billion people. In the small SE Asian nation of Timor-Leste, infection rates in some regions approach 70%, and the resulting anemia from these infections has a serious impact on quality of life. Health officials are concerned by a recent rise in Ivermectin-resistant cases in the isolated enclave of Oecussi, and are worried about these drug resistance genes spreading to the capital Dili, 165 km away. You genotype diploid female hookworms, Ancylostoma ceylanicum, from 100 patients in each location for a neutral locus with two alleles A1 & A2. You find the following genotypic count data:     A1/A1 A1/A2 A2/A2 Oecussi 36 48 16 Dili 9 42   3a. Use these data to calculate FST between these two populations.     3b. Assuming that these two populations are in drift/migration equilibrium, what is the effective number of migrants moving between them each generation

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Hookworms, parasitic nematodes transmitted through contact between bare feet and soil,
infect nearly a half billion people. In the small SE Asian nation of Timor-Leste, infection rates in
some regions approach 70%, and the resulting anemia from these infections has a serious impact
on quality of life. Health officials are concerned by a recent rise in Ivermectin-resistant cases in
the isolated enclave of Oecussi, and are worried about these drug resistance genes spreading to
the capital Dili, 165 km away. You genotype diploid female hookworms, Ancylostoma ceylanicum,
from 100 patients in each location for a neutral locus with two alleles A1 & A2.
You find the following genotypic count data:
 
  A1/A1 A1/A2 A2/A2
Oecussi 36 48 16
Dili 9 42  
3a. Use these data to calculate FST between these two populations.
 
 
3b. Assuming that these two populations are in drift/migration equilibrium, what is the effective
number of migrants moving between them each generation
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