Can someone help with this question? Hexokinase catalyzes the following reaction in glycolysis:Glucose + ATP -→• glucose-6-phosphate + ADPThe standard free-energy change for this reaction in the direction written is -16.7 kJ/mol.The concentrations of the related reaction components in the hepatocyte of a mammalian cell are:Glucose: 5 mMGlucose-6-phosphate: 0.083 mMATP: 1.85 mMADP: 0.14 mMWhat is the actual free-energy change for the reaction at body temperature (37 C)?-14.3 kJ/mol-33.3 kJ/mol+33.3 kJ/mol+14.3 kJ/mol Use the following table for all questions in the problem set related to glycolysis:TABLE 18.1 Reactions and Thermodynamics of GlycolysisAG"AGReactionEnzyme(k/mol)at 25°c(kJ/mol)HexokinaseGlucokinasea-D-Glucose + ATPt-=-16.7850-33.9*glucose-6-phosphate?- + ADP- + H*Glucose-6 phosphate²-=fructose-6-phosphate-Fructose-6-phosphate- + ATP-=fructose-1,6-bisphosphate- + ADP- + H*Fructose-1,6-bisphosphatedihydroxyacetone-P- + glyceraldehyde-3-P:-Dihydroxyacetone-P=glyceraldehyde-3-P-Glyceraldehyde-3-P- + P?- + NAD*=1,3-bisphosphoglycerate- + NADH + H*1,3-Bisphosphoglycerate + ADP-PhosphoglucoisomerasePhosphofructokinase+1.670.51-2.92-14.2310-18.8Fructose bisphosphatealdolase+23.96.43 X 10-3-0.23Triose phosphate isomeraseGlyceraldehyde-3-PdehydrogenasePhosphoglycerate kinase+7.560.0472+2.41+6.300.0786-1.29-18.92060+0.13-Pglycerate- + ATP-3-Phosphoglycerate =2phosphoglycerate2-Phosphoglycerate-=Phosphoglycerate mutase+4.40.169+0.83Enolase+1.80.483+1.1phosphoenolpyruvate-+ H,0Phosphoenolpyruvate- + ADP- + H* =Pyruvate + ATpt-Pyruvate + NADH + H*= lactate" + NAD*Pyruvate kinase-31.73.63 x 10-23.0Lactate dehydrogenase-25.22.63 x 10-14.8

The above reaction is the first step in glycolysis where one molecule of glucose is phosphorylated…

Hexokinase catalyzes the following reaction in glycolysis: Glucose + ATP-- glucose-6-phosphate + ADP The standard free-energy change for this reaction in the direction written is -16.7 kJ/mol. The concentrations of the related reaction components in the hepatocyte of a mammalian cell are: Glucose: 5 mM Glucose-6-phosphate: 0.083 mM ATP: 1.85 mM ADP: 0.14 mM What is the actual free-energy change for the reaction at body temperature (37 C)? -14.3 kJ/mol -33.3 kJ/mol +33.3 kJ/mol +14.3 kJ/mol

Hexokinase catalyzes the following reaction in glycolysis: Glucose + ATP-- glucose-6-phosphate + ADP The standard free-energy change for this reaction in the direction written is -16.7 kJ/mol. The concentrations of the related reaction components in the hepatocyte of a mammalian cell are: Glucose: 5 mM Glucose-6-phosphate: 0.083 mM ATP: 1.85 mM ADP: 0.14 mM What is the actual free-energy change for the reaction at body temperature (37 C)? -14.3 kJ/mol -33.3 kJ/mol +33.3 kJ/mol +14.3 kJ/mol

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter6: Basic Clinical Chemistry

Section6.5: Blood Glucose And Hemoglobin A1c

Problem 8RQ

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In the third step of glycolysis, the given reactions are coupled. reaction 1: fructose-6-phosphate + Pi ⟶ fructose-1,6-bisphosphate + H2O (Δ? = −28 kJ/mol) reaction 2: ATP + H2O ⟶ ADP + Pi (Δ? = +13.8 kJ/mol) Calculate the overall ΔG (kJ/mol) for the coupled reaction.
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