Here C has 2 alleles C1 and C2 and same with D allele. C1D1 are the haplotypes for both of the populations: C1 D1 C1D1 First Population 0.3 0.5 0.45 Second Population 0.5 0.2 0.15 1. find the linkage disequilibrium between C and D in first and second population 2. does first population has fewer or mare haplotypes than expected 3. Cosider the recombinantion fraction as 0.1. How many generation will linkage disequilibrium in first population take to be equal to the current value in second population
Evolutionary Genetics
Evolution is known as continuous changes that occur to adjust organisms in their changing environment over many generations. Various theories have been proposed to illustrate the origin of life and organic evolution. The most accepted one is the theory of natural selection by Charles Darwin. According to his postulate, organisms undergo a struggle for existence due to overproduction. To survive in nature, they acquire variations. The inheritable variations are selected by nature, and it leads to the survival of the fittest.
Phenotype Frequency
The majority of populations have a certain degree of variation in their genetic pools. Scientists can predict the genetic variation happening over time by measuring the amount of genetic variation in a population and these predictions assist them in gaining important insights into the processes that allow organisms to adapt to the environment or to develop into new species over generations. This process is referred to as the process of evolution.
Hardy Weinberg Equilibrium
The frequencies of allele and genotype were maintained constant from one generation to another due to the absence of other evolutionary forces. It is otherwise called the Hardy Weinberg principle the field of population genetics.
Here C has 2 alleles C1 and C2 and same with D allele. C1D1 are the haplotypes for both of the populations:
| C1 | D1 | C1D1 | |
| First Population | 0.3 | 0.5 | 0.45 |
| Second Population | 0.5 | 0.2 | 0.15 |
1. find the linkage disequilibrium between C and D in first and second population
2. does first population has fewer or mare haplotypes than expected
3. Cosider the recombinantion fraction as 0.1. How many generation will linkage disequilibrium in first population take to be equal to the current value in second population
A measure of the non-random relationship or relationship between alleles at two or more loci (gene locations) on a chromosome is referred to as linkage disequilibrium (LD). It demonstrates the manner in which, more frequently than would be predicted by chance, the existence or lack of a certain allele at one site is correlated with the presence or absence of a particular allele at another locus.
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