glycerol + ATP O glycerol-1-phosphate + ADP

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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3. A key step in the biosynthesis of triglycerides is the conversion of glycerol to glycerol-
1-phosphate by ATP
glycerol + ATP O glycerol-1-phosphate + ADP
At steady state in vivo [ATP] = 103 M and [ADP] = 104 M. The equilibrium value of the
ratio [glycerol-1-PJUglycerol] is 770 at 25° C and pH 7.
A. Calculate AG°298K (the standard value of AG at pH 7) and Keg for the reaction as
written.
B. The value of AG®298K for the reaction ADP + P, O ATP + H,O is -31.0 kJ mol1.
Using this information plus your answer for part (A.), calculate AGO298K and Keg for the
reaction
glycerol + phosphate O glycerol-1-P + H,0
Transcribed Image Text:3. A key step in the biosynthesis of triglycerides is the conversion of glycerol to glycerol- 1-phosphate by ATP glycerol + ATP O glycerol-1-phosphate + ADP At steady state in vivo [ATP] = 103 M and [ADP] = 104 M. The equilibrium value of the ratio [glycerol-1-PJUglycerol] is 770 at 25° C and pH 7. A. Calculate AG°298K (the standard value of AG at pH 7) and Keg for the reaction as written. B. The value of AG®298K for the reaction ADP + P, O ATP + H,O is -31.0 kJ mol1. Using this information plus your answer for part (A.), calculate AGO298K and Keg for the reaction glycerol + phosphate O glycerol-1-P + H,0
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