NameENRICHMENT ACTIVITY (continued)Genetics Problem Solving Crosses Involving Multiple Alleles25Step 4Combine the gamete genotypes of one parent with those of the other parent to show all possibleoffspring genotypes.14JAJA I^i|8 [+18 1BiStep 5 State the genotype and phenotype ratios of the offspring.1 : 1 Pi: 1118: 118 = 141, 141, 148, 14182 type A: 1 type AB: 1 type B = 1/2 type A, 14 type AB, 4 type BCHAPTEREXERCISESFor each exercise draw the Punnett square when appropriate and answer the questions in the spaces provided.1. A woman homozygous for type B blood marries a man who is heterozygous type A. What will be thepossible genotypes and phenotypes of their children?2. A man with type O blood marries a woman with type AB blood. What will be the possible genotypesand phenotypes of their children?3. A type B woman whose mother was type O marries a type O man. What will be the possible genotypesand phenotypes of their children?4. A type A woman whose father was type B marries a type B man whose mother was type A. What will betheir childrens' possible genotypes and phenotypes?5. What is the probability that a couple whose blood types are AB and O will have a type A child?6. A couple has a child with type A blood. If one parent is type O, what are the possible genotypes of theother parent? Crosses Involving Multiple AllelesIn previous activities, every gene was considered to have only two possiblealleles. For example, the alleles of the gene for plant height in peas are eithertall or short, and the alleles of the gene for fruit color in squash are eitheryellow or white. However, there are genes for which more than two differentalleles exist. When this is the case the alleles are referred to as multiple alleles.As you know, a diploid individual can carry only two alleles for any gene.This is because for each gene one allele is carried on each of the twochromosomes that constitute a pair of homologous chromosomes. But in apopulation of individuals, more than two alleles of a gene can exist. Forexample, one individual may have alleles 1 and 2 of a particular gene whileanother individual may have alleles 2 and 5 of that same gene. The best knownexample of multiple alleles involves the gene for blood type in humans. Thisgene has three different alleles and is located on chromosome 9, two copies ofwhich exist in all human body cells. The alleles of this gene are designated asfollows:I-codes for type A blood18-codes for type B bloodi-codes for type O bloodI and 18 are each dominant over i, but are not dominant over each other. Thepossible genotypes and corresponding blood types are as follows:genotype phenotype (blood type)iiStep 2|A|A18₁1818|A|BStep 3OSAMPLE PROBLEMA woman with type A blood whose father was type O married a man with type AB blood. What will be thepossible genotypes and phenotypes of their children?Step 1AABBABDetermine the genotypes of the parents.Type A woman with type O father iType AB man |A|BIX ABDetermine the gamete genotypes produced by each parent.Pii|A|B|A,18Set up a Punnett square using the gamete genotypes..|A18

Name: NameENRICHMENT ACTIVITY (continued)Genetics Problem Solving Crosses I
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Description: NameENRICHMENT ACTIVITY (continued)Genetics Problem Solving Crosses Involving Multiple Alleles25Step 4Combine the gamete genotypes of one parent with those of the other parent to show all possibleoffspring genotypes.14JAJA I^i|8 [+18 1BiStep 5 State