The ABO blood group in humans is controlled by a single locus with three different alleles. Homozygosity for lª produces type A blood. Homozygosity for 1³ produces type B blood. Homozygosity for 10 produces type O blood. Type AB blood is produced by the genotype 1A/IB. 10 is recessive to 1ª and 1³; thus, lª /1º gives type A blood and 1³ /10 gives type B blood. In the United States, the allele frequencies for the ABO alleles are given below. The Rh factor in blood typing also has multiple alleles, but the alleles can be classified into two types, positive and negative. Rh+ is dominant over Rh-. The allele frequencies of these alleles are also indicated below. The MN blood antigen trait is controlled by two codominant alleles at a single locus. Type M individuals are homozygous for the M allele, type MN individuals are heterozygous, and type N individuals are homozygous for the N allele (codominant). In the United States, the allele frequencies for this blood group are also indicated below. ABO [10] = 0.50 [IA] = 0.35 [1³] = 0.15 0.5 0.22 0.27 lolololol Rhesus 0.31 0.25 [Rh+] = 0.6 [Rh-] = 0.4 At what frequency would you expect to find type M blood among progeny from brother-sister mating? MN [M] = 0.5 N = 0.5

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The ABO blood group in humans is controlled by a single locus with three different alleles. Homozygosity for \( I^A \) produces type A blood. Homozygosity for \( I^B \) produces type B blood. Homozygosity for \( I^O \) produces type O blood. Type AB blood is produced by the genotype \( I^A / I^B \). \( I^O \) is recessive to \( I^A \) and \( I^B \); thus, \( I^A / I^O \) gives type A blood and \( I^B / I^O \) gives type B blood. In the United States, the allele frequencies for the ABO alleles are given below.

The Rh factor in blood typing also has multiple alleles, but these alleles can be classified into two types, positive and negative. Rh+ is dominant over Rh−. The allele frequencies of these alleles are also indicated below.

The MN blood antigen trait is controlled by two codominant alleles at a single locus. Type M individuals are homozygous for the M allele, type MN individuals are heterozygous, and type N individuals are homozygous for the N allele (codominant). In the United States, the allele frequencies for this blood group are also indicated below.

### Table of Allele Frequencies

| ABO          | Rhesus       | MN        |
|--------------|--------------|-----------|
| \( [I^O] \) = 0.50 | \( [Rh+] \) = 0.6 | [M] = 0.5 |
| \( [I^A] \) = 0.35 | \( [Rh-] \) = 0.4 | [N] = 0.5 |
| \( [I^B] \) = 0.15 |              |           |

### Question
At what frequency would you expect to find type M blood among progeny from brother-sister mating?

- ○ 0.5
- ○ 0.22
- ○ 0.27
- ○ 0.31
- ○ 0.25
Transcribed Image Text:The ABO blood group in humans is controlled by a single locus with three different alleles. Homozygosity for \( I^A \) produces type A blood. Homozygosity for \( I^B \) produces type B blood. Homozygosity for \( I^O \) produces type O blood. Type AB blood is produced by the genotype \( I^A / I^B \). \( I^O \) is recessive to \( I^A \) and \( I^B \); thus, \( I^A / I^O \) gives type A blood and \( I^B / I^O \) gives type B blood. In the United States, the allele frequencies for the ABO alleles are given below. The Rh factor in blood typing also has multiple alleles, but these alleles can be classified into two types, positive and negative. Rh+ is dominant over Rh−. The allele frequencies of these alleles are also indicated below. The MN blood antigen trait is controlled by two codominant alleles at a single locus. Type M individuals are homozygous for the M allele, type MN individuals are heterozygous, and type N individuals are homozygous for the N allele (codominant). In the United States, the allele frequencies for this blood group are also indicated below. ### Table of Allele Frequencies | ABO | Rhesus | MN | |--------------|--------------|-----------| | \( [I^O] \) = 0.50 | \( [Rh+] \) = 0.6 | [M] = 0.5 | | \( [I^A] \) = 0.35 | \( [Rh-] \) = 0.4 | [N] = 0.5 | | \( [I^B] \) = 0.15 | | | ### Question At what frequency would you expect to find type M blood among progeny from brother-sister mating? - ○ 0.5 - ○ 0.22 - ○ 0.27 - ○ 0.31 - ○ 0.25
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