From the above figure, you can conclude what about the process that allows the SARS CoV-2 virus entry into the cell? Options: The spike protein is not involved in cell entry, contrary to popular belief This is evidence for clathrin-mediated endocytosis as the entry method or SAR CoV-2 into the cell The spike protein interacts with clathrin directly to enter the cell The spike protein interacts with a human cell surface receptor
Please help me with this question. More than one answer may be correct. THe graph relating to the information is included below.
The above graph is looking at the relative entry of SARS-CoV2 isolated spike proteins into human cells in culture at two times points: before introduction of the virus to the cell culture (0 minute) and 5 minutes after introduction of the virus to the cell culture. CHC stands for "clathrin heavy chain" and siRNA stands for small interfering RNA, which is often used in experiments as an easy method to stop expression of a certain gene. So in this case, the CHC siRNA would stop cellular production of CHC. The control siRNA introduces a small RNA fragment that does not match any gene as a negative control. From the above figure, you can conclude what about the process that allows the SARS CoV-2 virus entry into the cell?
Options:
The spike protein is not involved in cell entry, contrary to popular belief
This is evidence for clathrin-mediated endocytosis as the entry method or SAR CoV-2 into the cell
The spike protein interacts with clathrin directly to enter the cell
The spike protein interacts with a human cell surface receptor
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