Assuming there are colon tumor samples, one from a HNPCC patient, and the other from a FAP patient. One group shows gross chromosomal abnormalities with chromosomal translocations, deletions, etc. The karyotype of the group, however, looks mostly normal, and similar to noncancerous samples. Which group is expected to carry loss-of-function mutations in MSH2 and MLH1 (DNA mismatch repair genes) as their primary driver mutations? FAP that has grossly abnormal karyotype HNPCC that has mostly normal karyotype FAP that has mostly normal karyotype

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Environmental health and hazards

An organism's environment is the environment in which it lives and has an impact on its well-being. The World Health Organization (WHO) defines environmental health as "those aspects of public health, such as quality of life, that are influenced by physical, chemical, biological, social, and psychosocial components in the environment." Environmental health is concerned with both natural and man-made settings in order to enhance public health. Environmental science, occupational medicine, toxicology, and epidemiology are the key subdisciplines of environmental health.