For the tetrapeptide KASE: a. Draw its complete protonic equilibria. Indicate the net charge of each form and encircle the zwitterionic form. b. Give the full name of the tetrapeptide. c. Calculate its IpH. d. If the tetrapeptide was subjected to electrophoresis using a buffer solution at pH 7, at which electrode it will migrate?
For the tetrapeptide KASE: a. Draw its complete protonic equilibria. Indicate the net charge of each form and encircle the zwitterionic form. b. Give the full name of the tetrapeptide. c. Calculate its IpH. d. If the tetrapeptide was subjected to electrophoresis using a buffer solution at pH 7, at which electrode it will migrate?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
For the tetrapeptide KASE:
a. Draw its complete protonic equilibria. Indicate the net charge of each form and encircle the zwitterionic form.
b. Give the full name of the tetrapeptide.
c. Calculate its IpH.
d. If the tetrapeptide was subjected to electrophoresis using a buffer solution at pH 7, at which electrode it will migrate?
Transcribed Image Text:amino acid
alanine
arginine
aspartate
asparagine
cysteine
glutamate
glutamine
glycine
histidine
isoleucine
leucine
lysine
methionine
phenylalanine
proline
serine
threonine
tryptophan
tyrosine
valine
pka1 (-CO₂H)
2.34
2.17
1.88
2.02
1.96
2.19
2.17
2.34
1.82
2.36
2.36
2.18
2.28
2.20
1.99
2.21
2.11
2.38
2.20
2.32
pKa values
pKa2 (-NH3*)
9.69
9.04
9.60
8.80
10.28
9.67
9.13
9.60
9.17
9.68
9.60
8.95
9.21
9.13
10.96
9.15
9.62
9.39
9.11
9.62
pKar (R group)
12.48
3.65
8.18
4.25
6.00
10.53
10.07
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