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For the same drug, what amino acids of an active site of an enzyme would interact with one of the carbonyl oxygen groups by H bonding? HO leucine O glutamine O phenylalanine valine S OH H + NH

For the same drug, what amino acids of an active site of an enzyme would interact with one of the carbonyl oxygen groups by H bonding? HO leucine O glutamine O phenylalanine valine S OH H + NH

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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**Question:** For the same drug, what amino acids of an active site of an enzyme would interact with one of the carbonyl oxygen groups by H bonding? **Chemical Diagram Description:** The image displays a chemical structure featuring several rings and functional groups. A key feature is the presence of carbonyl oxygen groups that can participate in hydrogen bonding. Notable elements include: - Aromatic rings, contributing to the molecule's stability. - A carbonyl group (C=O) which is likely a site for hydrogen bonding. - Functional groups such as a hydroxyl group (OH) and an amide group. **Answer Options:** - ○ leucine - ● glutamine - ○ phenylalanine - ○ valine The correct answer, indicated by the filled circle, is **glutamine**. This amino acid's side chain can form hydrogen bonds with carbonyl oxygen groups due to its amide functional group.
Transcribed Image Text:**Question:** For the same drug, what amino acids of an active site of an enzyme would interact with one of the carbonyl oxygen groups by H bonding? **Chemical Diagram Description:** The image displays a chemical structure featuring several rings and functional groups. A key feature is the presence of carbonyl oxygen groups that can participate in hydrogen bonding. Notable elements include: - Aromatic rings, contributing to the molecule's stability. - A carbonyl group (C=O) which is likely a site for hydrogen bonding. - Functional groups such as a hydroxyl group (OH) and an amide group. **Answer Options:** - ○ leucine - ● glutamine - ○ phenylalanine - ○ valine The correct answer, indicated by the filled circle, is **glutamine**. This amino acid's side chain can form hydrogen bonds with carbonyl oxygen groups due to its amide functional group.
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