For the amino acid arginine: Draw its complete protonic equilibria. Indicate the net charge of each form and encircle the zwitterionic form.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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For the amino acid arginine: Draw its complete protonic equilibria. Indicate the net charge of each form and encircle the zwitterionic form. Provide labels (A, B, C, etc.) for each form. b. Calculate the IpH of the amino acid. c. At what pH range(s) it can act as a buffer? d. What will be the predominant form(s) of the amino acid at pH (i) 1.5; (ii) 3.0; (iii) 4.5; (iv) 6.0; (v) 7.5 and (vi) 9.0?
amino acid
alanine
arginine
aspartate
asparagine
cysteine
glutamate
glutamine
glycine
histidine
isoleucine
leucine
lysine
methionine
phenylalanine
proline
serine
threonine
tryptophan
tyrosine
valine
pka1 (-CO₂H)
2.34
2.17
1.88
2.02
1.96
2.19
2.17
2.34
1.82
2.36
2.36
2.18
2.28
2.20
1.99
2.21
2.11
2.38
2.20
2.32
pKa values
pKa2 (-NH3*)
9.69
9.04
9.60
8.80
10.28
9.67
9.13
9.60
9.17
9.68
9.60
8.95
9.21
9.13
10.96
9.15
9.62
9.39
9.11
9.62
pKar (R group)
12.48
3.65
8.18
4.25
6.00
10.53
10.07
Transcribed Image Text:amino acid alanine arginine aspartate asparagine cysteine glutamate glutamine glycine histidine isoleucine leucine lysine methionine phenylalanine proline serine threonine tryptophan tyrosine valine pka1 (-CO₂H) 2.34 2.17 1.88 2.02 1.96 2.19 2.17 2.34 1.82 2.36 2.36 2.18 2.28 2.20 1.99 2.21 2.11 2.38 2.20 2.32 pKa values pKa2 (-NH3*) 9.69 9.04 9.60 8.80 10.28 9.67 9.13 9.60 9.17 9.68 9.60 8.95 9.21 9.13 10.96 9.15 9.62 9.39 9.11 9.62 pKar (R group) 12.48 3.65 8.18 4.25 6.00 10.53 10.07
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