For each of the labelled chirality centers, determine the R or S configuration. Br H3C CH2CH3 ((CH3)3 B D E CH2OH OF CH,Br CI SCH3 ОН I H 4-CEC OH

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**Q4.5 E**

![Chemical structure diagram with labeled carbon atoms]

**Question:**  
What is the configuration for the carbon atom labeled E?

- O R
- O S
- O Neither R nor S

**Q4.6 F**

![Chemical structure diagram with labeled carbon atoms]

**Question:**  
What is the configuration for the carbon atom labeled F?

- O R
- O S
- O Neither R nor S

**Explanation of Diagram:**

The diagram presents a complex organic molecule with several carbon atoms labeled from A to J. The focus is on the stereochemistry of the carbon atoms labeled E and F. The molecule includes various functional groups such as alkenes, alcohols, and bromides. To determine the R or S configuration, one must consider the priority of the substituents attached to these carbon atoms according to the Cahn-Ingold-Prelog priority rules.
Transcribed Image Text:**Q4.5 E** ![Chemical structure diagram with labeled carbon atoms] **Question:** What is the configuration for the carbon atom labeled E? - O R - O S - O Neither R nor S **Q4.6 F** ![Chemical structure diagram with labeled carbon atoms] **Question:** What is the configuration for the carbon atom labeled F? - O R - O S - O Neither R nor S **Explanation of Diagram:** The diagram presents a complex organic molecule with several carbon atoms labeled from A to J. The focus is on the stereochemistry of the carbon atoms labeled E and F. The molecule includes various functional groups such as alkenes, alcohols, and bromides. To determine the R or S configuration, one must consider the priority of the substituents attached to these carbon atoms according to the Cahn-Ingold-Prelog priority rules.
**Q4 R and S Configurations**

For each of the labeled chirality centers, determine the R or S configuration.

The diagram shows a complex organic molecule with multiple chirality centers denoted by letters A through J. The structure includes various functional groups:

- A bromine (Br) atom is attached at chirality center A.
- A chiral center labeled B is shown with a methyl group (CH₃) and a hydrogen in specific orientations (wedge and dash notation).
- The chiral centers C, D, E, F, G, H, I, and J are positioned along the carbon backbone with differing attached groups, including ethyl groups (CH₂CH₃), a tert-butyl group (C(CH₃)₃), hydroxyl groups (OH), a thioester (SCH₃), and a cyclopropane (triangle symbol for I).
- There are double bonds present, indicated by lines, and elements like chlorine (Cl) are attached within the structure.
 
The task involves analyzing each chiral center to determine if it is in either R (rectus) or S (sinister) configuration based on priority rules in stereochemistry.
Transcribed Image Text:**Q4 R and S Configurations** For each of the labeled chirality centers, determine the R or S configuration. The diagram shows a complex organic molecule with multiple chirality centers denoted by letters A through J. The structure includes various functional groups: - A bromine (Br) atom is attached at chirality center A. - A chiral center labeled B is shown with a methyl group (CH₃) and a hydrogen in specific orientations (wedge and dash notation). - The chiral centers C, D, E, F, G, H, I, and J are positioned along the carbon backbone with differing attached groups, including ethyl groups (CH₂CH₃), a tert-butyl group (C(CH₃)₃), hydroxyl groups (OH), a thioester (SCH₃), and a cyclopropane (triangle symbol for I). - There are double bonds present, indicated by lines, and elements like chlorine (Cl) are attached within the structure. The task involves analyzing each chiral center to determine if it is in either R (rectus) or S (sinister) configuration based on priority rules in stereochemistry.
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