Following the revised diagnosis at age 17, she received additional treatment. How does this treatment, and her response to it, strengthen the evidence that this patient really had characteristics of both type 1 and type 2 diabetes mellitus? Explain your answer.
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Following the revised diagnosis at age 17, she received additional treatment. How does this
treatment, and her response to it, strengthen the evidence that this patient really had
characteristics of both type 1 and type 2 diabetes mellitus? Explain your answer.
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- Discuss the aetiology and pathogenesis of type 2 diabetes mellitus. In your answer, make clear the term ‘insulin resistance’ by providing an example to illustrate your understanding of this occurrence. Determine whether the C-peptide test would be useful in diagnosing type 2 diabetesType- 2 diabetes mellitus is: 1.both a secondary pathology and usually the result of inappropriate hormone secretion 2.both a secondary pathology and usually the result of abnormal target cell responsiveness 3.usually the result of inappropriate hormone secretion 4.a secondary pathology 5.usually the result of abnormal target cell responsivenessWhich of the following best describes the role of the hexosamine pathway in the pathogenesis of the chronic complications of diabetes mellitus? Question 79 options: a) It involves irreversible binding of glucose to proteins, lipids and nucleic acids which damages components of the microcirculation leading to retinopathy, etc. b) It promotes the O-linked glycosylation of proteins and transcription factors, resulting in altered gene expression contributing to insulin resistance & cardiovascular complications c) It promotes the synthesis of DAG which increases pro-inflammatory gene expression and endothelial ET-1 production resulting in blood flow abnormalities d) It leads to intracellular accumulation of osmotically active sorbitol and fructose which damages Schwann cells, erythrocytes and the lens of the eye
- Diabetes insipidus has been identified in two males. One person did not have the condition until he had a stroke. The other had lived with the condition his whole life, and despite the existence of normal ADH receptors, it had never reacted to exogenous ADH. What might be the cause of the two men's diabetes insipidus? Provide your references.Discuss the relationship between diabetes mellitus and cardiovascular disease. What dietary measures can be taken to decrease the risks associated with the two disease processes in a patient who has been diagnosed with both?Fatima is a 43 year old lady with a diagnosis bipolar affective disorder and usually manages her Type 1 diabetes with minimal support. She is currently hypomanic and reports that she has not slept for more than 3 hours in the last 5 days. A) Explain your understanding of Type 1 and 2 diabetes. B) Why might Fatima's current hypomanic presentation present additional risks to her physical health? C) What interventions would you suggest in this situation? Please justify your answer.
- Compare and contrast the pathophysiology and treatment of type I versus type II diabetes.The patient has a history of diabetes mellitus type 1. What effect might her prednisone prescription have on her diabetes? What actions are needed to reduce this effect?In addition to symptoms of diabetes, all the following are criteria recommended by the American Diabetes Association for use in the diagnosis of Diabetes Mellitus EXCEPT: O Random plasma glucose concentration > 180 mg/dL. O Fasting plasma glucose > 126 mg/dL. O 2-Hour glucose > 200 mg/dL during a 2 hour post prandial glucose test O Hemoglobin A1C > 6.5%
- Which of the following statements about type 1 diabetes pathophysiology are true? Select all that apply A) The immune system begins to attack pancreatic B-cells in response to elevated blood sugar B) The activated immune system destroys pancreatic ß cells C) Thelper cells are activated resulting in production of autoantibodies from self-reactive plasma cells D) The body does not produce self-reactive cytotoxic T cellsIdentify the possible etiologies (causes) of Diabetes mellitus. SELECT ALL THAT APPLY A. Reduced effects of insulin on cells of the body B. Increased digestion of carbs in the pancreas C. Pregnancy D. Loss of insulin production by the pancreas.Lifestyle modification could be very useful for this patient. What would these modificationsinclude and would they help resolve the type 1, type 2, or both types of diabetes mellitus that this patient is experiencing? Explain your answer.