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A dietary deficiency of iodine will lead to which of the following?
Question 89 options:
a)
Decreased production of thyrotropin-releasing hormone (TRH)
b)
An increased secretion of thyroid-stimulatory hormone (TSH)
c)
A direct effect on the synthesis of thyroglobulin on ribosomes
d)
Decreased gene expression due to the inability of receptors to bind to DNA
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- Which of the following would result in an INCREASE in BLOOD glucose levels ? choose all of the options that apply. a)AKT mutation that makes it inactive b)A mutation in TBC1D4 that renders it inactive at all times. c)RAB10 has a mutation that boosts its GTPase activity. d) GSK3beta has a mutation that makes it always off. e) The insulin receptor has a mutation that precludes dimerization.Which of the following is important in signal transduction triggered by hormones?a) Phosphatidylinositol and its derivativesb) Phosphatidylserine and its derivativesc) Phosphatidylglycerol and its derivativesd) PhosphatidylethanolamineWhat is the likely function of the cytosolic cAMP in this transduction pathway? Question 16 options: a) It is a competitive inhibitor of the protein kinase. b) It is a hormone. c) It is a messenger RNA. d) It is a coenzyme. e) It is a second messenger.
- Which 2 endocrine glands exert the most control over blood calcium level:a) anterior pituitary and adrenal cortex b) thyroid and ovaries c) adrenal cortex and thyroid d) parathyroid and anterior pituitary e) thyroid and parathyroidWhat is the role of calcium at the synaptic terminal?Explain the active site theory of enzyme functioning?Question 1 AAcrobatta AÇ . Which of the following does not stimulate the 1a-hydroxylase enzyme required for Vitamin D activation? a) Parathyroid Hormone b) Prolactin c) Hypocalcemia d) Calcitonin e) Hypophosphataemia 2113 NEAR EAST UNIVERSITY COyokimya.VETWhat chemical is the structural basis of the bile salts, Vitamin D, and all of the steroid hormones to include estrogen, progesterone, and testosterone? A) Cholesterol B) Arginine C) Glucose D) Acetyl CoA E) Glucose-6-dehydrogenase
- For each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). A. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). B. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). C. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).Insulin dependent diabetes is caused by the degeneration of beta cells due to a _________.a) gene b) alleles c) defective gene d) gene set72. Which of the following hormones promotes protein synthesis in skeletal muscle and lipolysis in adipocytes? A) Epinephrine B) Glucagon C) Growth hormone D) Insulin E) Thyroid hormone
- Now answer the following questions: 1. Is this patient experiencing a disorder affecting anaerobic or aerobic metabolism? a) disorder affecting anaerobic metabolism. b) disorder affecting aerobic metabolism. c) None of them d) Both 2. You decide to perform assays to check the activity of one or more metabolic enzymes in the red blood cells. Which enzyme(s) would you check? a) Amylase b) Enzymes of pentose phosphate pathways c) Transaminase enzymes d) hexokinase, phosphofructokinase, and pyruvate kinaseVon Gierke’s disease is a rare genetic disorder that results in a deficiency of glucose-6-phosphatase. Symptoms ketoacidosis, a buildup of glycogen in the liver, and lactate buildup. Why does this glycogen storage disease not affect the brain? a) The brain is able to still perform glycolysis effectively b) None of the above c) In the event of hypoglycemia, the brain is able to utilize other sources of energy to produce ATP d) The brain is able to metabolize lactate, which is present in high concetrations.One such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below: 1) Provide a brief explanation as to why ligand binding to proteins must be a reversible process. 2) Calculate the dissociation constant (Kd) for the hormone binding to each of the three proteins. 3) Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?
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