Following formation of a double-stranded break, enzymes process the dsDNA end to form single-stranded DNA as shown in Fig. 11-4b. Does it matter if resection occurs in the 5’ to 3’ direction or the 3’ to 5’ direction? Explain why or why not.
Following formation of a double-stranded break, enzymes process the dsDNA end to form single-stranded DNA as shown in Fig. 11-4b. Does it matter if resection occurs in the 5’ to 3’ direction or the 3’ to 5’ direction? Explain why or why not.
Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Following formation of a double-stranded break, enzymes process the dsDNA end to form single-stranded DNA as shown in Fig. 11-4b. Does it matter if resection occurs in the 5’ to 3’ direction or the 3’ to 5’ direction? Explain why or why not.
Transcribed Image Text:The image depicts the structure of DNA strands, emphasizing the complementary base pairing and antiparallel orientation of the strands.
**Explanation of the Diagram:**
1. **Top Left:**
- Two grey single-stranded DNA sequences labeled "A" are displayed.
- One strand is oriented 5' to 3', while the complementary strand runs 3' to 5', indicating the antiparallel nature of DNA.
2. **Top Right:**
- Two grey single-stranded DNA sequences labeled "B" are shown.
- Similar to the "A" strands, each strand pair exhibits antiparallel orientation, with one strand running 5' to 3' and the complementary strand running 3' to 5'.
3. **Bottom:**
- The bottom section presents a complete double-stranded DNA molecule shown in blue.
- Labeled "a" and "b," these strands are paired and run in opposite directions to each other, further showcasing the antiparallel orientation.
- The arrows within the strands indicate the directionality from 5' to 3' and 3' to 5'.
This visualization helps illustrate how DNA strands pair through complementary base pairing and how their antiparallel structure is central to DNA replication and function.
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