flouroquinolones like levofloxacin (of the underlying structure) are antibiotics with broad antibacterial spectrum widely used nowadays to treat bacterial infections. unfortunately, they form water insoluble complexes in the GIT when taken orally together with divalent metal supplements like iron as sulfate salt [in the second oxidation state a. draw the structure of the resulted metals complexes with levofloxacine. b. expect the electronic configuration showing the complexation orbitals and sharing for each metal case c. how many coordination covalent bond are expected form such complexation and the type of hybridization expected d. what would be the influence of such complexation on the bioavailability of both the metals and the antibiotic e. which functional groups in the levofloxacin structure are expected to be the ligands in the resulted complexes. f. which type of chelating agent levofloxine would be expected in these cases.
flouroquinolones like levofloxacin (of the underlying structure) are antibiotics with broad antibacterial spectrum widely used nowadays to treat bacterial infections. unfortunately, they form water insoluble complexes in the GIT when taken orally together with divalent metal supplements like iron as sulfate salt [in the second oxidation state
a. draw the structure of the resulted metals complexes with levofloxacine.
b. expect the electronic configuration showing the complexation orbitals and sharing for each metal case
c. how many coordination covalent bond are expected form such complexation and the type of hybridization expected
d. what would be the influence of such complexation on the bioavailability of both the metals and the antibiotic
e. which
f. which type of chelating agent levofloxine would be expected in these cases.
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