Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2. 6. Figure 1 shows that remdesivir "mimics" an important component of RNA replication. Which specific component of RNA replication has a structure like that of remdesivir? 7. Propose a hypothesis about how remdesivir might inhibit the virus's replication process.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Remdesivir is an antiviral drug used to treat SARS-CoV-2 infections. It is a broad-spectrum antiviral, meaning it
has activity against many different viruses. Remdesivir can be incorporated into a new RNA chain as a virus
replicates and can interfere with the viral replication machinery.
Template RNA
Elongation
New RNA
SARS-CoV-2 RNA polymerase
Template groove
Nucleotide
entrance
Nucleotides
Remdesivir
Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2.
6. Figure 1 shows that remdesivir "mimics” an important component of RNA replication. Which specific
component of RNA replication has a structure like that of remdesivir?
7. Propose a hypothesis about how remdesivir might inhibit the virus's replication process.
Transcribed Image Text:Remdesivir is an antiviral drug used to treat SARS-CoV-2 infections. It is a broad-spectrum antiviral, meaning it has activity against many different viruses. Remdesivir can be incorporated into a new RNA chain as a virus replicates and can interfere with the viral replication machinery. Template RNA Elongation New RNA SARS-CoV-2 RNA polymerase Template groove Nucleotide entrance Nucleotides Remdesivir Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2. 6. Figure 1 shows that remdesivir "mimics” an important component of RNA replication. Which specific component of RNA replication has a structure like that of remdesivir? 7. Propose a hypothesis about how remdesivir might inhibit the virus's replication process.
Expert Solution
Step 1 Introduction:

Remdesivir is an antiviral drug used for the treatment of SARS-CoV-2 infections. Its antiviral activity has been attributed to its ability to mimic a critical component of RNA replication.

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