Explain why a strain of yeast with a defect in the enzyme alcohol dehydrogenase can grow well under aerobic conditions, but not under anaerobic conditions. The yeast strain grows well when aerobic because acetaldehyde is quickly converted to lactate. The yeast strain uses CO2 to generate NAD+ when aerobic, but GAPDH needs NADH when anaerobic. The yeast strain grows equally well under aerobic and anaerobic, but polyphenol is lethal to this strain. The yeast strain cannot oxidize NADH to generate NAD+ for the GAPDH reaction when anaerobic. The yeast strain needs to generate ethanol in order to stimulate the PFK- 1 reaction when anaerobic.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Explain why a strain of yeast with a defect in the enzyme alcohol
dehydrogenase can grow well under aerobic conditions, but not under
anaerobic conditions.
The yeast strain grows well when aerobic because acetaldehyde is
quickly converted to lactate.
The yeast strain uses CO₂ to generate NAD+ when aerobic, but GAPDH
needs NADH when anaerobic.
The yeast strain grows equally well under aerobic and anaerobic, but
polyphenol is lethal to this strain.
The yeast strain cannot oxidize NADH to generate NAD+ for the GAPDH
reaction when anaerobic.
The yeast strain needs to generate ethanol in order to stimulate the PFK-
1 reaction when anaerobic.
Transcribed Image Text:+ Explain why a strain of yeast with a defect in the enzyme alcohol dehydrogenase can grow well under aerobic conditions, but not under anaerobic conditions. The yeast strain grows well when aerobic because acetaldehyde is quickly converted to lactate. The yeast strain uses CO₂ to generate NAD+ when aerobic, but GAPDH needs NADH when anaerobic. The yeast strain grows equally well under aerobic and anaerobic, but polyphenol is lethal to this strain. The yeast strain cannot oxidize NADH to generate NAD+ for the GAPDH reaction when anaerobic. The yeast strain needs to generate ethanol in order to stimulate the PFK- 1 reaction when anaerobic.
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