EXPLAIN WHY? A drug is has half life of 7 h and volume of distribution 20 L was given by contant infusion at a rate of 40 mg/h. Assuming one compartment model, the steady state concentration is……? A) 10.2 mg/mL B) 20.2 mg/L C) 20.2 mg/mL D) 15.5 mg/mL E) 15.5 mg/L

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EXPLAIN WHY?

A drug is has half life of 7 h and volume of distribution 20 L
was given by contant infusion at a rate of 40 mg/h.
Assuming one compartment model, the steady state
concentration is……?
A) 10.2 mg/mL
B) 20.2 mg/L
C) 20.2 mg/mL
D) 15.5 mg/mL
E) 15.5 mg/L

A drug with half live of 10 h and Vd 15 L was given by
constant infusion to achieve required steady state
concentration of 0.5 mcg/ml.
• How much time it requires to achieve 95% of desired
Css?

 

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