Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Explain the steps involved in using Koch's postulate to establish the link between a suspected microorganism and disease.
Expert Solution
Step 1
Koch's postulates
These are four criteria designed to establish a causative relationship between a microbe and a disease.
The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884.
These postulates are universal for all microorganisms except for viruses, Mycobacterium leprae, Treponema pallidum.
Step 2
The 4 Koch postulates are :-
- The microorganism must be found in diseased but not healthy individuals.
- The microorganism must be cultured from the diseased individual.
- The cultured microorganism must cause disease in the test animal
- The microorganism must be re-isolated from the inoculated, diseased test animal and matched to the original microorganism.
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