Examine the peptide.Thr‑Lys‑Pro‑Ile‑Val‑Ala‑Pro‑Met‑Glu‑Tyr‑Gly‑LysEstimate the net charge on the peptide at pH 7.Estimate the net charge on the peptide at pH 12. GroupAcidBaseTypical pk,Terminal a-carboxyl3.1groupAspartic acidGlutamic acid4.1N.Histidine6.0+ H-N-NTerminal a-amino group8.0H.CysteineH'-S8.3+ H-N-NTHHLysine10.8Тугosine10.9HHN-HH.NArginine12.5N-HH'N-HH'O-U

The net charge of peptide molecule depends upon the charge on the amino acids side chain, N-terminal…

Answered: Examine the peptide.…

Examine the peptide. Thr‑Lys‑Pro‑Ile‑Val‑Ala‑Pro‑Met‑Glu‑Tyr‑Gly‑Lys Estimate the net charge on the peptide at pH 7. Estimate the net charge on the peptide at pH 12.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

100%

Examine the peptide.

Thr‑Lys‑Pro‑Ile‑Val‑Ala‑Pro‑Met‑Glu‑Tyr‑Gly‑Lys

Estimate the net charge on the peptide at pH 7.

Estimate the net charge on the peptide at pH 12.

Group
Acid
Base
Typical pk,
Terminal a-carboxyl
3.1
group
Aspartic acid
Glutamic acid
4.1
N.
Histidine
6.0
+ H
-N
-N
Terminal a-amino group
8.0
H.
Cysteine
H'
-S
8.3
+ H
-N
-N
TH
H
Lysine
10.8
Тугosine
10.9
H
H
N-H
H.
N
Arginine
12.5
N-H
H'
N-H
H'
O-U

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