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Eventually when glucose consumed is so low gluconeogenesis is also inhibited. Explain how this happens.
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- In the absence of food consumption, the rate of gluconeogenesis (GNG) tends to increase. Explain why this occurs and describe the range of substrates for GNG as fasting continues beyond 18 hours. asapFatty acids appear to stimulate insulin secretion to a much greater extent when glucose is also present. Why is this significant?Explain why triglycerides have a glucose-sparing effect.
- Is glycogen is broken down to release glucose. True or false. Explain.Define Glycolysis and Gluconeogenesis. How GLYCOLYSIS and GLUCONEOGENESIS does reciprocally regulated in the body? Explain it.Indicate whether the following metabolic processes primarily occur during the FED STATE or FASTED STATE. 1. Release of insulin 2. Release of glucagon 3. Glycolysis 4. Glycogenesis 5. Gluconeogenesis 6. Lipogenesis 7. Glycogenolysis 8. Lipolysis 9. Glucose release 10. Glucose uptake
- Elevated liver NADH levels favors gluconeogenesis.Explain this statement.Mutations in glucokinase which lower the kcat for the enzyme or elevate the Km for glucose result in mild to moderate elevation of blood glucose. Explain how these mutations cause diabetes-like symptoms in patients.Is the statement much of the regulation of gluconeogenesis a result of the inhibition of glycolysis incorrect or correct?