Errors in splicing are implicated in cancers and other human diseases. What kinds of mutations might lead to splicing errors? Think of different possible outcomes if splicing errors occur.

Q: List five types of cancer in which ncRNAs can be involved.

A: Non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Epigenetic related…

Q: Explain the process of pre-mRNA splicing in nuclear genes.

A: Pre-messenger ribonucleic acid (mRNA) splicing is essential process for the gene expression in…

Q: What is a disorder caused by errors in transcription? What kind of error is involved?

A: Transcription is defined as the process by which the information present in a DNA strand is copied…

Q: Explain three types of post-transcriptional modifications to RNA.

A: Post-transcriptional alteration or co-transcriptional adjustment is a bunch of organic cycles normal…

Q: Define mutation. Then describe the three basic types of mutation (substitutions, insertions, and…

A: A mutation is an alteration in the DNA sequence that mainly arises during the replication of DNA or…

Q: In prokaryotes, the promoter contains a -35 and -10 region upstream of the transcription start site.…

A: Promoter is the sequence in DNA where RNA polymerase is recruited. This is present before the…

Q: What could be the effect  of a base substitution which prevents post-transcriptional removal of an…

A: A base substitution is a genetic mutation where a single nucleotide base is changed in the sequence…

Q: What is the Results of tra splicing in the absence of Sxl protein?

A: sxl or sex lethal gene is found in Drosophila melanogaster. sxl gene in Drosophila regulates the sex…

Q: What is post-translational modification? Describe two specific post-translational modifications and…

A: The translation is the process in which proteins are synthesized via mRNA. The process of…

Q: What is RNA editing, how can it increase the number of proteins that can be formed from a single…

A: RNA editing also participated in the variations of proteomics sequence. In many types of cancers…

Q: which enzyme is used in the processing of miRNAs that are encoded in the genome but not in the…

A: Introduction Short interfering RNA or siRNA along with miRNA with DICER enzyme form the silencing…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: Why are histone modifying enzymes important?

A: Chromosomes are thread-like structures that are present in the nucleus of the cell. The basic unit…

Q: Name the three main stages of pre-mRNA processing. Explain the importance of each of the stages of…

A: Pre-mRNA, or precursor mRNA, is an immature RNA molecule that is transcribed from a gene in the cell…

Q: Explain in detail the role of super-enhancers. Give some examples. How the super-enhancers can be…

A: There are trillions of cells in the physical structure. They give the body structure, absorb…

Q: post-transcriptional modifications that occur in mRNA and tRNA.

A:

Q: The ability to selectively modify the genome in the mouse has revolutionized mouse genetics. Outline…

A: Molecular biology's applications include the development of new protein products, illness prevention…

Q: Topic: Splicing a. What is the big picture of splicing and what is the importance of this concept…

A: RNA splicing is a process that cuts the, non-coding sequences of genes (introns) from pre-mRNA and…

Q: three different types of loss of function mutations and in each case explain how the mutation exerts…

A: A mutation is any alteration of the base sequence of the DNA or RNA. Since mutation alters the base…

Q: How can we identify histone modifications?

A: Histones are the class of proteins which are associated with the DNA in the nucleus and aids in the…

Q: What happens when a nonsense mutation is introduced into a transposon's gene encoding transposase?

A: A non-sense mutation is a mutation that terminates translation earlier resulting in the formation of…

Q: Describe the connection between silent mutations and redundancy of the code.  ​

A: BASIC INFORMATION  MUTATION  It is a discontinuous change in genes which leads to change in genotype…

Q: Why is RNA splicing important to cellular processes and protein synthesis?

A: As per the central dogma of molecular biology, DNA contains the information needed to synthesize…

Q: RNA splicing

A: Most eukaryotic cells undergo post-transcriptional modification, which involves chemically altering…

Q: What general characteristics are found in many transposable elements?

A: Transposable elements are also known as jumping genes or transposons. A transposon is a segment of…

Q: Explain why STR mutations are found at a much higher frequency than single nucleotide changes?

A: STR means single tandem repeat, and the mutation in the STR segments is at a very high rate .

Q: Describe the effects of intron phase on alternative splicing with diagram

A: Alternative splicing involves the removal of introns from the mRNA transcript as introns are the…

Q: What is the importance of alternative splicing? How is this an efficient method of translating…

A: Alternative splicing, or elective RNA splicing, or differential grafting, is an elective splicing…

Q: Albinism is a condition where individuals can't make melanin pigment. The affected gene encodes for…

A: Albinism is a group of inherited disorders which can lead to no production of melanin pigment due to…

Q: Which of the following would not be the consequence of alternative splicing? Two genes to express…

A: Alternative splicing is the method of producing differentially spliced mRNAs by choosing alternative…

Q: TRUE OR FALSE Errors in transcription can lead to silent mutations encoding the same amino acid or…

A: Silent mutations are the type of mutations in which base substitution has no effect in…

Q: Alternative splicing allows an organism to express different versions of a gene in different cells…

A: Splicing  The removal of introns from the pre mature RNA. The intros are the non coding portion of…