which enzyme is used in the processing of miRNAs that are encoded in the genome but not in the processing of exogenously added siRNAs?

Q: What process in mRNA folding leads to sensitivity to pain due to an effect on the COMT gene?

A: COMT is catechol-o- methyltransferase protein presence required for pain sensitivity.

Q: Match each of the following descriptions to the type of regulatory RNA affecting a "target" gene…

A: Of course! Let's break down each match:This regulatory RNA may increase transcription of the target…

Q: What could be the effect  of a base substitution which prevents post-transcriptional removal of an…

A: A base substitution is a genetic mutation where a single nucleotide base is changed in the sequence…

Q: What is the difference between an miRNA and an siRNA. How dothese ncRNAs affect mRNAs?

A: Ribonucleic acid or RNA is a polymeric molecule of nucleic acid which is essential in various…

Q: What is the main difference between Sirna and miRNA?

A: RNA (ribonucleic acid) is a polymer of nucleotides and is composed of a pentose sugar, a nitrogen…

Q: What enzymes are involved in production of both miRNA and siRNA?

A: RNA is one of the major genetic materials present in living and non-living (such as viruses) systems…

Q: What are the 3 ways in which sRNAs regulate the translation of mRNAs?

A: Gene regulation involves the expression of certain genes at a time out of all the genes present in…

Q: What is a potential link between prostate cancer and miRNA-101?

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Q: Explain how some lncRNAs serve as molecular decoys for RNA-binding proteins and miRNAs.

A: LncRNAs or Long noncoding RNAs are pervasive genes in important class that are involved in various o…

Q: How do ncRNAs regulate gene expression, and how would their pervasiveness affect the Central Dogma?

A: The non-coding region of RNAs [ncRNAs] is a part of the RNA molecule which was not involved in the…

Q: How does miRNA act similar to RNA¡ and does the process of the mechanism differ?

A: RNAi is the biological process  in which short RNA molecules suppresses gene expression in a…

Q: A gene contains eight sites where alternativesplicing is possible. Assuming that the splicing…

A: according to the question, A gene contains eight sites where alternative splicing is possible:

Q: Do you think it would be easier to mutate the GR receptor or treat someone with a miRNA to overcome…

A: MicroRNAs are a grade of non-coding RNAs which plays vital role in managing gene expression. Large…

Q: Pre-mRNAs in mitochondria are converted to maturemRNAs through which process?

A: A precursor mRNA is the molecule in the primary transcript which gets converted to mRNA(messenger)…

Q: How do miRNAs and siRNAs target RNAs for destruction?

A: miRNAs (microRNAs) and siRNAs (small interfering RNAs) are noncoding RNAs that play important roles…

Q: Which RNA conformation favors transcription—the form with the antiterminator stem-loop or the form…

A: The process of transcription allows the formation of RNA from DNA with help of DNA-dependent RNA…

Q: Why are miRNAs called noncoding RNAs? Explain how they participate in gene regulation.

A: Answer- miRNA are non coding RNA because it does not code for any amino acid to form proteins.

Q: Why do trans-sRNAs often require a chaperone protein?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Where does miRNA fit into gene expression?

A: Gene is the primary unit of heredity of all living beings. It undergoes some modification process…

Q: Define about primary miRNAs (pri-miRNAs) ?

A: MicroRNAs (miRNAs) are small regulatory RNAs derived from stem-loop sections of original transcripts…

Q: What has to happen for the expression of two differentgenes on two different chromosomes to be…

A: A gene is a specific sequence of nucleotides in DNA or RNA that is usually found on a chromosome and…

Q: What are snRNPs? What is their role in the processing of eukaryotic mRNAs?

A: DNA is the genetic information carrier in almost all organisms except for a few RNA viruses. DNA is…

Q: Consider the CT/CGRP example of alternative splicing. Which different types of alternative splicing…

A: Alternative splicing is a technique that allows messenger RNA (mRNA) to control the production of…

Q: Splicing machinery must recognize three portions of the precursor RNA molecule: the 5’ splice site,…

A: The spliceosome, a huge ribonucleprotein complex, is responsible for removing introns from…

Q: Splicing regulatory (SR) proteins bind at exon to recruit U1snRNP and U2 snRNP during RNA splicing.…

A: There are few important points about splicing apparatus are as follows: The central component of…

Q: How many different polypeptides can be producedthrough alternative splicing of the same pre-mRNA?

A: Maturation of eukaryotic mRNA often entails the removal of RNA sequences (introns or intervening…

Q: Why is an NFR needed at the core promoter for transcription to occur?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Some eukaryotic mRNAs contain an AU-rich element in the 3’ untranslated region.  What would be the…

A: The regulation of gene expression is done by the pre-mRNA processing and degradation of mRNA. The…

Q: What is miRNA replacement therapy? Describe three examples of this treatment approach.

A: A Gene is a unit of heredity containing the fundamental information of life as a distinct sequence…

Q: What is the difference between how miRNA stops gene expression and how siRNA does?

A: The siRNA is obtained from the double stranded RNA after splicing of cutting by Dicer enzyme. But…

Q: What is the importance of alternative splicing? How is this an efficient method of translating…

A: Alternative splicing, or elective RNA splicing, or differential grafting, is an elective splicing…

Q: RNAi may be directed by small interfering RNAs (siRNAs) or microRNAs (miRNAs); how are these…

A: RNA (ribonucleic acid) which is essential in various processes of gene expression.  ▪︎ mainly three…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.