Epoxides are highly strained and can alleviate the strain by reacting under acidic and basic conditions to give different regiochemical and stereochemical products. In this epoxide tutorial, we will cover 1. ring opening of unsubstituted epoxide 2. which nucleophiles will open an epoxide 3. regiochemical and stereochemical results of basic ring opening of asymmetrical epoxides 4. regiochemical and stereochemical results of acidic ring opening Step 3: If the nucleophilic attack takes place on a chiral epoxide, an inversion of configuration is observed. Consider the epoxide ring-opening of a chiral epoxide. 1. NaSH ? 2. H₂O Select the product or products of the reaction. SH SH SH JOH ...OH OH OH .....SH

Epoxides are highly strained and can alleviate the strain by reacting under acidic and basic conditions to give different regiochemical and stereochemical products. In this epoxide tutorial, we will cover 1. ring opening of unsubstituted epoxide 2. which nucleophiles will open an epoxide 3. regiochemical and stereochemical results of basic ring opening of asymmetrical epoxides 4. regiochemical and stereochemical results of acidic ring opening Step 3: If the nucleophilic attack takes place on a chiral epoxide, an inversion of configuration is observed. Consider the epoxide ring-opening of a chiral epoxide. 1. NaSH ? 2. H₂O Select the product or products of the reaction. SH SH SH JOH ...OH OH OH .....SH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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