2. During glycolysis, glucose is converted to pyruvate. Pyruvate then is converted to Acetyl coA and enters the citricacid cycle. Per one (1) glucose molecule that undergoes glycolysis and TCA cycle, complete the table belowEquivalence in ATPProducts from glycolysis1. ATP2. _NADHPyruvateATP: producedATPАТРATPS3.ATPS producedАТРАТРProducts from TCAEquivalence in ATPNADH5. _FADH26. GTP4.ATPSATPSATPSАТРTOTAL ATP Produced7.ATP

Glycolysis and TCA cycle are metabolic pathways in the cell. In glycolysis one molecule of glucose…

Answered: During glycolysis, glucose is converted…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Consider a 24:1 △cis-9 fatty acid in the mitochondrion. For each fatty acid given, determine the following. Gross ATP from b-oxidation cycles Gross ATP from acetyl CoA produced Gross ATP from conversion of propionyl CoA (if applicable) Total number of ATP deducted Total net ATP
Match the coenzymes and/or substrates with their corresponding glycolytic enzymes. Note that an enzyme can match with more than one coenzyme or substrate in the list. ATP NAD+ Dihydroxyacetone phosphate A. Glucose 1-dehydrogenase B. Phosphofructokinase-1 C. Glyceraldehyde 3-phosphate dehydrogenase D. ATPase E. Triose phosphate isomerase
Describe the movement of energy during acetyl–CoA formationand the citric acid cycle.
High amount of citrate decreases the activity of fructose 1,6-bisphosphatase. True or False
In type I diabetes mellitus, excessive production of acetyl-CoA may surpass the body’s capacity to oxidize it. As a result, acetoacetate, β-hydroxybutyrate, and acetone (ketone bodies) accumulate. When generated in large amounts, blood pH falls, thereby reducing the capacity of red blood cells to carry oxygen. Explain in general terms how high concentrations of ketone bodies may result in a fatal coma.
Consider the reaction shown, which of the following conditions is most likely to lead to the activation of pyruvate dehydrogenase? high concentrations of acetyl-CoA high concentrations of NADH high concentrations of NAD+ high concentrations of CO2
Can you please pick the right answer in each parentheses (a) to (e)? Coenzymes are nonprotein compounds that are required for the activity of certain enzymes. One critical coenzyme central to metabolism is NAD+. In fact it is one of 5 coenzymes required by (a)< "pyruvate dehyrogenase" vs "citrate synthase" > , the critical enzyme for producing Acetyl-CoA. NAD+ is synthesized from (b)< "niacin (vitamin B3)" vs "acetate" > as was discovered to be critical for health by two American scientists, (c)<"Joseph Goldberger and Conrad Elvehjem" vs "Linus Pauling and Eric Lander"> , in the early 20th century. Dietary lack of this critical molecule produces pellagra, characterized by the following symptoms: (d)<"skin inflammation, dementia, diarrhea" vs "chorea-like movement">. People with these problems were found in parts of the U.S. where diets lacked vegetables and consisted principally of corn. Interestingly, soaking the corn in (e)<"salt water" vs…
A fatty acid (a long straight-chain carboxylic acid with an even number of carbons) is metabolized to acetyl- CoA, which can then enter the citric acid cycle to be further metabolized (Section 24.9). A fatty acid with anodd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are needed to convert it to succinyl-CoA, acompound that can enter the citric acid cycle. Write the two enzyme-catalyzed reactions and include the names of the required coenzymes.
A series of chemical reactions convert a polypeptide into 13 acetyl CoAs. This acetyl COA goes into the citric acid cycle and then all of the NADH and FADH2 produced are covnerted to ATP by oxidative phosphorylation. How many total ATP is produced from this acetyl COA including the citric acid cycle and oxidative phosphorylation? Your Answer:
Name the three processes circled, say where they occur/how they relate, and what their significant contribution is?
Malate synthase, an enzyme of the glyoxylate cycle, catalyzes the condensa- tion of glyoxylate with acetyl-CoA. Which enzyme of the citric acid cycle carries out a similar reaction? Would you expect the binding of glyoxylate and acetyl-CoA to malate synthase to be sequential? Why?
The pyruvate dehydrogenase complex catalyzes the synthesis of acetyl-CoA, a very important molecule in cellular metabolism. The reaction catalyzed by the pyruvate dehydrogenase enzyme complex is shown below. This reaction is tightly regulated, because it is essentially irreversible. Which of the following conditions is most likely to lead to the inhibition of pyruvate dehydrogenase in cells? (select two answers) High concentrations of acetyl-CoA High concentrations of pyruvate High concentrations of NADH High concentrations of NAD+ High concentrations of CoA

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During glycolysis, glucose is converted to pyruvate. Pyruvate then is converted to Acetyl coA and enters the citric acid cycle. Per one (1) glucose molecule that undergoes glycolysis and TCA cycle, complete the table below