Drug G is available as a weak acid (WA) and has two salt forms. Their properties are listed below: Log Ko/w Aqueous solubility Very slightly soluble Slightly soluble Sparingly soluble Drug G forms MW WA 416 Da 3.3 Sodium Salt 460 Da | 2.8 Potassium Salt 520 Da 1.9 Drug G is available in the following formulations: Oral Solution Oral Suspension Immediate release tablet Based on the information provided, answer the following questions: 20. Which form of the drug is present in the Oral solution dosage form and why? 21. Which dosage form has the fastest onset of action? 22. Which dosage form has the smallest particle size? 23. Which dosage form will have the highest patient compliance?
Drug G is available as a weak acid (WA) and has two salt forms. Their properties are listed below: Log Ko/w Aqueous solubility Very slightly soluble Slightly soluble Sparingly soluble Drug G forms MW WA 416 Da 3.3 Sodium Salt 460 Da | 2.8 Potassium Salt 520 Da 1.9 Drug G is available in the following formulations: Oral Solution Oral Suspension Immediate release tablet Based on the information provided, answer the following questions: 20. Which form of the drug is present in the Oral solution dosage form and why? 21. Which dosage form has the fastest onset of action? 22. Which dosage form has the smallest particle size? 23. Which dosage form will have the highest patient compliance?
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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
Transcribed Image Text:**Drug G Information and Formulations**
**Drug G is available as a weak acid (WA) and has two salt forms. Their properties are listed below:**
| Drug G forms | MW | Log Ko/w | Aqueous solubility |
|----------------|--------|----------|-------------------------|
| WA | 416 Da | 3.3 | Very slightly soluble |
| Sodium Salt | 460 Da | 2.8 | Slightly soluble |
| Potassium Salt | 520 Da | 1.9 | Sparingly soluble |
**Drug G is available in the following formulations:**
- Oral Solution
- Oral Suspension
- Immediate release tablet
**Based on the information provided, answer the following questions:**
20. Which form of the drug is present in the Oral solution dosage form and why?
21. Which dosage form has the fastest onset of action?
22. Which dosage form has the smallest particle size?
23. Which dosage form will have the highest patient compliance?
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