ReferencesThe Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation The mostcommon partners in the reaction are a nucleophilic donor (such as a cyclic ketone, a B-keto ester, an enamine, or a B-diketone) and an aB-unsaturated ketoneacceptor. The product is a substituted 2-cyclohexenone derivative.Draw the structures of the nucleophilic 6-ketro ester and theaB-unsaturated ketone acceptor that were conbined in a Robinson annulation to give the followingproductPhCO,Et• Draw the B-keto ester as an ethyl ester,P.Activate(Previous OwsGoithSertinc

The retrosynthesis of the given compound gives us the nucleophilic beta-keto ester and alpha-beta…

Answered: Draw the structures of the nucleophilic…

Draw the structures of the nucleophilic B-keto ester and the aB-unsaturated ketone acceptor that were combined in a Robinson annulation to give the following product: Ph ČO,Et

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter24: Catalytic Carbon-carbon Bond Formation

Section: Chapter Questions

Problem 24.9P

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