**Problem Explanation:**You are tasked with drawing the predominant form of glutamic acid at a pH of 8.4. The pKa of the side chain is 4.1. It is important to include the correct stereochemistry when illustrating the molecular structure.**Diagram Explanation:**The diagram displays the molecular structure of glutamic acid with its chemical groups:- An amine group: \( \text{NH}_2 \)- A carboxylic acid group: \( \text{COOH} \)- Another carboxylic acid group as part of the side chain**Instructions:**1. Determine the ionization state based on the given pH and pKa.2. Depict the molecule considering the given pH of 8.4.3. Show proper stereochemistry in your drawing.**Note:** The pH of 8.4 is higher than the pKa of the side chain (4.1), indicating the side chain carboxylic acid will be deprotonated. You can use this information to deduce how the structure of glutamic acid changes at this pH level. Make sure the drawing reflects these characteristics in the designated area.

If the pH is greater than pKa then deprotonation occurs and it exists in deprotonation form. While…

Answered: Draw the predominant form of glutamic…

Draw the predominant form of glutamic acid at pH = 8.4. The pKa of the side chain is 4.1. Include proper stereochemistry. HO H₂N, pH = 8.4 Drawing OH Q

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Coding Strand of DNA

When pointing to DNA transcription, the coding strand is found to be the DNA strand whose base sequence is indistinguishable from the base sequence of the RNA transcript developed. It is this strand that comprises the codons, while the non-coding strand comprises the anti-codons.

Nucleotide

Both DNA and RNA are composed of organic molecules known as nucleotides. Hence, nucleotides are known as the basic building blocks of nucleic acids. These substances play a role in various processes such as cell signalling, enzyme reactions, metabolism, and so on.

Structure of Cytosine

Cytosine is among the five primary nitrogenous bases of which DNA and RNA and are being used in storage and transportation of genetic makeup within a cell. Adenine, guanine, thymine as well as uracil are the remaining four nucleobases.

Question

**Problem Explanation:**

You are tasked with drawing the predominant form of glutamic acid at a pH of 8.4. The pKa of the side chain is 4.1. It is important to include the correct stereochemistry when illustrating the molecular structure.

**Diagram Explanation:**

The diagram displays the molecular structure of glutamic acid with its chemical groups:
- An amine group: \( \text{NH}_2 \)
- A carboxylic acid group: \( \text{COOH} \)
- Another carboxylic acid group as part of the side chain

**Instructions:**

1. Determine the ionization state based on the given pH and pKa.
2. Depict the molecule considering the given pH of 8.4.
3. Show proper stereochemistry in your drawing.

**Note:** The pH of 8.4 is higher than the pKa of the side chain (4.1), indicating the side chain carboxylic acid will be deprotonated.

You can use this information to deduce how the structure of glutamic acid changes at this pH level. Make sure the drawing reflects these characteristics in the designated area.

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