Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
Do sister chromatid exchanges (SCEs) produce
new allelic combinations ?
Sister chromatid exchange (SCE):
a. SCEs are reciprocal exchanges of DNA segments between sister chromatids of duplicated metaphase chromosomes.
b. It is a natural phenomenon that occurs frequently in somatic and germline cells.
c. They are classified into spontaneous SCEs observed in normal cells and induced SCEs noticed in cancer or normal treated cells. This process takes place in the synthetic phase of the cell cycle.
d. It is an excellent tool for qualitative and quantitative assessment of DNA damage and has been used for three decades.
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