Direction of new synthesis Ticket-out: Newly synthesized strand Something is wrong with replisome shown in this cartoon – what do you think it is? Can you spot the problem? DNA polymerase III RNA primer DNA helicase Leading strand template DNA gyrase 5' Tau Parental DNA RNA primer DNA polymerase III DNA primase Newly synthesized strand Lagging strand template Single-strand DNÃ-binding proteins Direction of new synthesis

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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something is wrong with replisome shown in this cartoon -what do you think it is? 

Can you spot the problem? 

DNA Replication – Replisome
Replisome is a replication complex consisting of multiple proteins involved in DNA
replication at the replication fork.
Direction of
new synthesis
Ticket-out:
Newly synthesized strand
Something is wrong with replisome shown
in this cartoon – what do you think it is?
Can you spot the problem?
DNA polymerase III
5'
3'
RNA primer
DNA helicase
Leading strand template
DNA gyrase
5'
Tau
Parental DNA
RNA primer
DNA polymerase II
DNA primase
3'
5'
5'
Newly synthesized strand
Lagging
strand
Single-strand
DNA-binding
proteins
template
Direction of
new synthesis
Transcribed Image Text:DNA Replication – Replisome Replisome is a replication complex consisting of multiple proteins involved in DNA replication at the replication fork. Direction of new synthesis Ticket-out: Newly synthesized strand Something is wrong with replisome shown in this cartoon – what do you think it is? Can you spot the problem? DNA polymerase III 5' 3' RNA primer DNA helicase Leading strand template DNA gyrase 5' Tau Parental DNA RNA primer DNA polymerase II DNA primase 3' 5' 5' Newly synthesized strand Lagging strand Single-strand DNA-binding proteins template Direction of new synthesis
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